Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 7/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.33 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | SMO | Q99835 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8104039 | 0.91 | RAB9A (0.35) | PSMB5MCHR1MAPTALDH1A1MAP2K2 | |
| SCHEMBL8120742 | 0.83 | MAOB (0.36) | — | |
| SCHEMBL8112930 | 0.79 | ALDH1A1 (0.35) | PSMB5MCHR1MAPTALDH1A1MAP2K2 | |
| SCHEMBL8104610 | 0.79 | POLB (0.35) | KMT2ARORCGAA | |
| SCHEMBL8113212 | 0.77 | MAPT (0.38) | PSMB5MCHR1MAPTALDH1A1LMNA | |
| SCHEMBL8113483 | 0.77 | NPC1 (0.35) | PSMB5MCHR1MAPTALDH1A1MAPK1 | |
| SCHEMBL8104707 | 0.74 | MCHR1 (0.47) | PSMB5MCHR1MAPTALDH1A1MAPK1 | |
| SCHEMBL8118826 | 0.74 | MAPT (0.38) | PSMB5MCHR1MAPTALDH1A1LMNA | |
| SCHEMBL8104401 | 0.72 | MCHR1 (0.38) | PSMB5MCHR1MAPTALDH1A1MAPK1 | |
| SCHEMBL8112413 | 0.72 | NLRP3 (0.36) | PSMB5MCHR1MAPTALDH1A1MAP2K2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020434-A1 | 3-AMIDINOANILINE DERIVATIVES, ACTIVATED BLOOD COAGULATION FACTOR X INHIBITORS, AND INTERMEDIATES FOR PRODUCING BOTH | Kissei Pharmaceutical Co., Ltd. (JP) | 2000-07-19 | — | — | EP | disclosed |