SCHEMBL810409

SCHEMBL810409

C=Cc1ccc(C(C)Cl)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.52
TSHR P16473 1/20 0.40
HDAC8 Q9BY41 2/20 0.39
TYR P14679 1/20 0.38
PTGS2 P35354 2/20 0.36
TDP1 Q9NUW8 2/20 0.35
TAS1R3 Q7RTX0 2/20 0.33
TAS1R1 Q7RTX1 2/20 0.33
TP53 P04637 1/20 0.32
CHRNB2 P17787 1/20 0.32
CHRNB4 P30926 1/20 0.32
CHRNA3 P32297 1/20 0.32
CHRNA7 P36544 1/20 0.32
CHRNA4 P43681 1/20 0.32
TRPA1 O75762 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MAPK1 P28482 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8446629 0.81 RXRA (0.46) CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4
SCHEMBL1264527 0.80 ALDH1A1 (0.58) ALDH1A1TSHRHDAC8TYRTDP1
SCHEMBL1647492 0.80 ALDH1A1 (0.58) ALDH1A1TSHRHDAC8TYRPTGS2
SCHEMBL367595 0.80 TYR (0.58) ALDH1A1TSHRHDAC8TYRPTGS2
SCHEMBL6281528 0.80 ALDH1A1 (0.58) ALDH1A1TSHRHDAC8TYRPTGS2
SCHEMBL1140933 0.80 ALDH1A1 (0.58) ALDH1A1TSHRHDAC8TYRPTGS2
SCHEMBL2865480 0.79 ADRB2 (0.41) ALDH1A1TSHRTYRTDP1TRPA1
SCHEMBL22820010 0.78 ALDH1A1 (0.55) ALDH1A1TSHRHDAC8TYRPTGS2
Methane SCHEMBL11025053 0.78 TYR (0.56) ALDH1A1TSHRHDAC8TYRPTGS2
SCHEMBL394726 0.78 ALDH1A1 (0.55) ALDH1A1TSHRHDAC8TYRPTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5663260-A Hyperbranched copolymers from AB monomers and C monomers CORNELL RESEARCH FOUNDATION, INC. (US) 1997-09-02 US claimed
US-5587441-A Hyperbranched polymers from AB monomers CORNELL RESEARCH FOUNDATION, INC. (US) 1996-12-24 US claimed
US-5587446-A Hyperbranched polymers from AB monomers CORNELL RESEARCH FOUNDATION, INC. (US) 1996-12-24 US claimed
CN-119735766-A Method for preparing cyclic polymer at high concentration and prepared cyclic polymer 清华大学 2025-04-01 CN disclosed
CN-119735748-A Preparation method of polymer with ring-chain hybridization structure and polymer with ring-chain hybridization structure 清华大学 2025-04-01 CN disclosed
CN-114835854-A Ionic liquid copolymer and method for preparing cyclic carbonate by using same 中国科学院兰州化学物理研究所 2022-08-02 CN disclosed
EP-3610263-B1 METHOD FOR PREPARING HIGHLY POROUS POLYMER PARTICLES FOR DIAGNOSTIC APPLICATIONS ROCHE DIAGNOSTICS GMBH (DE) 2021-03-24 EP disclosed
WO-2020201089-A1 TRANSITION METAL CHELATING BEADS ROCHE DIAGNOSTICS GMBH (DE) 2020-10-08 WO disclosed
WO-2019141779-A1 HYPERCROSSLINKING WITH DIAMINE CROSSLINKERS F. HOFFMANN-LA ROCHE AG (CH) 2019-07-25 WO disclosed
EP-2506357-B1 Separation membrane for direct liquid fuel cell and method for producing same TOKUYAMA CORP (JP) 2015-06-17 EP disclosed
US-20130190473-A1 TONER FOR ELECTROSTATIC IMAGE DEVELOPMENT KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2013-07-25 US disclosed
US-5118430-A Polar phenoplast of the resol type and a copolymer crosslinkable with resols E. I. DU PONT DE NEMOURS AND COMPANY 1992-06-02 US disclosed
EP-0470105-A1 AQUEOUS VULCANIZING ADHESIVE. HENKEL KGAA (DE) 1992-02-12 EP disclosed
EP-0415729-A2 Vinylphenyl compound, process for the production thereof, polymerizable composition containing same, and crosslinked polymer formed therefrom TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1991-03-06 EP disclosed
WO-1990012847-A1 AQUEOUS VULCANIZING ADHESIVE HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1990-11-01 WO disclosed
EP-0345455-A2 Composition for the surface treatment of polymer fibres Henkel Kommanditgesellschaft auf Aktien (DE) 1989-12-13 EP disclosed
CN-1037750-A Polymer fiber surface treatment agent HENKEL KGAA (DE) 1989-12-06 CN disclosed
EP-0161373-B1 AQUEOUS ADHESIVE FOR BONDING RUBBER BY VULCANISATION TO A SUBSTRATE Henkel Kommanditgesellschaft auf Aktien (DE) 1988-03-02 EP disclosed
EP-0161373-A1 Aqueous adhesive for bonding rubber by vulcanisation to a substrate Henkel Kommanditgesellschaft auf Aktien (DE) 1985-11-21 EP disclosed
US-4483962-A TERPOLYMER OF 2,8-DIHALO-1,3-BUTADIENE, MONOALKENYL AROMATIC ALKYL HALIDE, AND UNSATURATED ACID MONOMER LORD CORPORATION (US) 1984-11-20 US disclosed