Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8104888 | 0.85 | PTK2B (0.54) | HSD17B10LMNACYP1A2CYP2C19CYP3A4 | |
| SCHEMBL8121943 | 0.84 | MAPK1 (0.43) | ALOX15MAPK1HSD17B10LMNACYP1A2 | |
| SCHEMBL8121709 | 0.84 | HSD17B10 (0.54) | ALOX15HSD17B10LMNACYP1A2CYP3A4 | |
| SCHEMBL8205625 | 0.77 | HSD17B10 (0.67) | ALOX15MAPK1HSD17B10LMNACYP1A2 | |
| SCHEMBL29666095 | 0.77 | HSD17B10 (0.67) | ALOX15MAPK1HSD17B10LMNACYP1A2 | |
| SCHEMBL12430328 | 0.77 | LMNA (0.57) | ALOX15MAPK1HSD17B10LMNACYP1A2 | |
| SCHEMBL8107951 | 0.77 | RAB9A (0.49) | HSD17B10CYP1A2CYP2C19GAACYP2C9 | |
| SCHEMBL8116713 | 0.76 | NPSR1 (0.47) | MAPK1HSD17B10LMNACYP1A2CYP2C19 | |
| SCHEMBL2442267 | 0.76 | KDM4E (0.65) | ALOX15MAPK1HSD17B10LMNACYP1A2 | |
| SCHEMBL29483352 | 0.76 | KDM4E (0.65) | ALOX15MAPK1HSD17B10LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114546-A | Aminomethylene derivatives and ultraviolet absorbent comprising thereof | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0950655-A1 | AMINOMETHYLENE DERIVATIVES AND ULTRAVIOLET ABSORBER COMPRISING THE SAME | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 1999-10-20 | — | — | EP | disclosed |