Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 2/20 | 0.36 |
| ▸ | MMP3 | P08254 | 2/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4379250 | 0.91 | HTT (0.39) | SIGMAR1ALDH1A1KDM4EALOX15L3MBTL1 | |
| SCHEMBL4382430 | 0.88 | CTSK (0.33) | — | |
| SCHEMBL8105600 | 0.83 | CYP19A1 (0.36) | SIGMAR1 | |
| SCHEMBL19210356 | 0.81 | SIGMAR1 (0.54) | SIGMAR1ABCB1ALDH1A1TDP1KDM4E | |
| SCHEMBL4381406 | 0.79 | CYP19A1 (0.32) | — | |
| SCHEMBL8116500 | 0.79 | HRH3 (0.38) | — | |
| SCHEMBL9119464 | 0.77 | CYP19A1 (0.46) | ALDH1A1MMP13KMT2A | |
| SCHEMBL9119587 | 0.75 | CYP19A1 (0.49) | ALDH1A1MAPK1KMT2A | |
| SCHEMBL4376567 | 0.74 | LMNA (0.34) | ALDH1A1KMT2A | |
| SCHEMBL8118972 | 0.73 | HMOX1 (0.34) | SIGMAR1L3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760811-A1 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H 3? (ANT)AGONISTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1997-03-12 | — | — | EP | claimed |