Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 2/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.34 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.33 |
| ▸ | CCR4 | P51679 | 2/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8113170 | 0.89 | TSHR (0.39) | TSHRCCR4 | |
| Diclosulam SCHEMBL116344 | 0.85 | GNRHR (0.35) | TSHRCCR4 | |
| SCHEMBL8848572 | 0.81 | GNRHR (0.34) | SCN1ASCN5ASCN8ATSHRACLY | |
| SCHEMBL8113251 | 0.80 | LMNA (0.37) | TSHR | |
| SCHEMBL910274 | 0.79 | GAA (0.42) | TSHRACLYCCR4 | |
| Diclosulam SCHEMBL2231960 | 0.78 | CA2 (0.33) | TSHR | |
| SCHEMBL4890265 | 0.77 | WDR5 (0.39) | ACLYCCR4 | |
| SCHEMBL118467 | 0.77 | WDR5 (0.39) | ACLYCCR4 | |
| SCHEMBL26838562 | 0.77 | CCR4 (0.34) | SCN1ASCN5ASCN8ATSHRCCR4 | |
| SCHEMBL8111629 | 0.77 | F7 (0.32) | TSHRACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114580-A | N-arylsulfilimine compounds and their use as catalysts in the preparation of N-arylarylsulfonamide compounds | DOW AGROSCIENCES LLC (US) | 2000-09-05 | — | — | US | disclosed |
| EP-0888297-B1 | N-ARYLSULFILIMINE COMPOUNDS AND THEIR USE AS CATALYSTS IN THE PREPARATION OF N-ARYLARYLSULFONAMIDE COMPOUNDS | DOW AGROSCIENCES LLC (US) | 2000-08-30 | — | — | EP | disclosed |
| US-5973148-A | N-arylsulfilimine compounds and their use as catalysts in the preparation of N-arylarylsulfonamide compounds | DOW AGROSCIENCES LLC (US) | 1999-10-26 | — | — | US | disclosed |