Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 4/20 | 0.68 |
| ▸ | FAAH | O00519 | 1/20 | 0.67 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.66 |
| ▸ | HPGD | P15428 | 4/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.66 |
| ▸ | PHGDH | O43175 | 6/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19357112 | 0.84 | PHGDH (0.79) | MGLLFAAHNCOA3ALDH1A1HPGD | |
| SCHEMBL4696938 | 0.83 | HPGD (0.72) | ALDH1A1HPGDPHGDHKDM4ETSHR | |
| Morpholino(Phenyl)Methanethione SCHEMBL9180076 | 0.82 | MGLL (0.79) | MGLLFAAHNCOA3ALDH1A1HPGD | |
| (4-Bromophenyl)(Morpholino)Methanethione SCHEMBL8424996 | 0.81 | MGLL (1.00) | MGLLFAAHNCOA3ALDH1A1HPGD | |
| SCHEMBL8495017 | 0.80 | MAPT (0.51) | MGLLALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL8115934 | 0.80 | ALDH1A1 (1.00) | MGLLALDH1A1HPGDHSD17B10ALOX15 | |
| SCHEMBL9792249 | 0.79 | KMT2A (0.70) | MGLLFAAHNCOA3ALDH1A1HPGD | |
| (4-Chlorophenyl)(Morpholino)Methanethione SCHEMBL9268856 | 0.79 | ALDH1A1 (1.00) | MGLLFAAHNCOA3ALDH1A1HPGD | |
| SCHEMBL7964773 | 0.77 | TSHR (0.79) | ALDH1A1HPGDPHGDHKDM4ETSHR | |
| Terephthalic Acid SCHEMBL28115441 | 0.77 | MAPT (0.56) | ALDH1A1HPGDPHGDHKDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0649843-B1 | THIAZOLINE DERIVATIVE | TAISHO PHARMACEUTICAL CO LTD (JP) | 2000-09-06 | — | — | EP | disclosed |
| US-5478945-A | Fibrinogen receptor antagonism and cell adhesion factor antagonism | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1995-12-26 | — | — | US | disclosed |
| EP-0649843-A1 | THIAZOLINE DERIVATIVE | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1995-04-26 | — | — | EP | disclosed |