Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | PHGDH | O43175 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.45 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KMO | O15229 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4696938 | 0.81 | HPGD (0.72) | MAPTHPGDPHGDHTSHRKMT2A | |
| Hydrochloric Acid SCHEMBL3315179 | 0.81 | LMNA (0.58) | MAPTHPGDTSHRF10ALDH1A1 | |
| SCHEMBL8923922 | 0.80 | GSK3B (0.65) | MAPTHPGDPHGDHKMT2APOLB | |
| SCHEMBL15651912 | 0.80 | MGLL (0.44) | MAPTHPGDPHGDHTSHRKMT2A | |
| SCHEMBL10131844 | 0.80 | MGLL (0.68) | MAPTHPGDPHGDHTSHRKMT2A | |
| SCHEMBL8108872 | 0.80 | MGLL (0.68) | MAPTHPGDPHGDHTSHRKMT2A | |
| SCHEMBL26482357 | 0.77 | ITGB3 (0.43) | HPGDPHGDHTSHRALDH1A1ALOX15 | |
| SCHEMBL7964773 | 0.76 | TSHR (0.79) | MAPTHPGDPHGDHTSHRKMT2A | |
| SCHEMBL19832853 | 0.76 | MGLL (0.41) | MAPTHPGDPHGDHTSHRKMT2A | |
| SCHEMBL13185332 | 0.76 | FKBP1A (0.51) | MAPTHPGDKMT2ATDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866592-A | Fibrinogen receptor antagonist and pharmaceutical compositions comprising the same | NIPPON STEEL CORPORATION (JP) | 1999-02-02 | — | — | US | disclosed |