Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | C1S | P09871 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 6/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 6/20 | 0.36 |
| ▸ | HPN | P05981 | 1/20 | 0.36 |
| ▸ | LTK | P29376 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6246471 | 0.81 | MAPT (0.42) | MAPTKDM4EALDH1A1GAAHPGD | |
| SCHEMBL3559657 | 0.81 | ALDH1A1 (0.54) | MAPTKDM4EALDH1A1GAAHPGD | |
| SCHEMBL11678330 | 0.78 | HCRTR1 (0.44) | MAPTKDM4EALDH1A1GAAHPGD | |
| SCHEMBL752611 | 0.77 | F2 (0.48) | MAPTKDM4EALDH1A1HPGDTSHR | |
| SCHEMBL932848 | 0.76 | ALOX15 (0.53) | MAPTKDM4EALDH1A1HPGDNPC1 | |
| Hydrochloric Acid SCHEMBL6341904 | 0.75 | BLM (0.50) | MAPTKDM4EALDH1A1HPGDTSHR | |
| SCHEMBL995326 | 0.75 | LTA4H (0.55) | MAPTKDM4EALDH1A1GAAHPGD | |
| SCHEMBL10495281 | 0.74 | F2 (0.55) | MAPTKDM4EALDH1A1HPGDTSHR | |
| SCHEMBL8578012 | 0.74 | LTA4H (0.45) | MAPTKDM4EALDH1A1GAAHPGD | |
| SCHEMBL1023432 | 0.74 | ALDH1A1 (0.42) | MAPTKDM4EALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6020488-A | Small molecule inhibition of RNA/ligand binding | SCRIPTGEN PHARMACEUTICALS INC. (US) | 2000-02-01 | — | — | US | disclosed |
| EP-0833824-A2 | SMALL MOLECULE INHIBITION OF RNA/LIGAND BINDING | SCRIPTGEN PHARMACEUTICALS, INC. (US) | 1998-04-08 | — | — | EP | disclosed |
| US-5668165-A | TREATMENT OF HIV INFECTIONS | SCRIPTGEN PHARMACEUTICALS, INC. (US) | 1997-09-16 | — | — | US | disclosed |
| WO-1996040668-A2 | SMALL MOLECULE INHIBITION OF RNA/LIGAND BINDING | SCRIPTGEN PHARMACEUTICALS, INC. (US) | 1996-12-19 | — | — | WO | disclosed |