Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.48 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | MYC | P01106 | 1/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11801296 | 0.84 | KDM4E (0.44) | ALOX15LMNAKDM4EGPR35FTO | |
| SCHEMBL6732189 | 0.84 | HPGDS (0.53) | ALOX15LMNAKDM4EALDH1A1MEN1 | |
| SCHEMBL1023432 | 0.83 | ALDH1A1 (0.42) | ALOX15LMNAKDM4EALDH1A1FTO | |
| SCHEMBL3559657 | 0.83 | ALDH1A1 (0.54) | KDM4EALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL11678330 | 0.83 | HCRTR1 (0.44) | LMNAKDM4EALDH1A1L3MBTL1MAPT | |
| SCHEMBL27204316 | 0.83 | BAZ2B (0.53) | LMNAKDM4EALDH1A1L3MBTL1MAPT | |
| SCHEMBL1823757 | 0.82 | GPR35 (0.52) | ALOX15LMNAKDM4EALDH1A1GPR35 | |
| SCHEMBL7159232 | 0.82 | G6PD (0.49) | ALOX15LMNAKDM4EALDH1A1GPR35 | |
| SCHEMBL4596567 | 0.82 | KDM4E (0.51) | ALOX15LMNAKDM4EALDH1A1GPR35 | |
| SCHEMBL7125127 | 0.82 | DHODH (0.49) | ALOX15LMNAKDM4EALDH1A1GPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 216 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105669506-B | A kind of synthetic method of 2 thiophenyl benzoic acid | 温州大学 | 2018-02-06 | — | — | CN | claimed |
| US-9656871-B2 | Edge-functionalized graphitic material through mechanochemical process and manufacturing method thereof | UNIST (ULSAN NATIONAL INSTITUTE OF SCIENCE AND TECHNOLOGY) (KR) | 2017-05-23 | — | — | US | claimed |
| CN-105669506-A | Synthetic method of 2-thiophenylbenzoic acid | 温州大学 | 2016-06-15 | — | — | CN | claimed |
| EP-2733116-A1 | GRAPHITE HAVING EDGES FUNCTIONALIZED BY A MECHANICAL-CHEMICAL TECHNIQUE, AND METHOD FOR MANUFACTURING SAME | UNIST Academy-Industry Research Corporation (KR) | 2014-05-21 | — | — | EP | claimed |
| CN-103355294-A | O-(4-fluorine) thiophenyl benzoic acid water dispersible granule and preparation method thereof | UNIV NANKAI | 2013-10-23 | — | — | CN | claimed |
| US-20130018204-A1 | EDGE-FUNCTIONALIZED GRAPHITIC MATERIAL THROUGH MECHANOCHEMICAL PROCESS AND MANUFACTURING METHOD THEREOF | UNIST ACADEMY-INDUSTRY RESEARCH CORPORATION (KR) | 2013-01-17 | — | — | US | claimed |
| CN-101525333-B | Synthesis method of metixene hydrochloride | UNIV EAST CHINA NORMAL | 2011-04-27 | — | — | CN | claimed |
| CN-101525333-A | Synthesis method of metixene hydrochloride | UNIV EAST CHINA NORMAL | 2009-09-09 | — | — | CN | claimed |
| WO-2009055631-A1 | CALCILYTIC COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-04-30 | — | — | WO | claimed |
| EP-0481522-B1 | Novel mercaptoacetylamide derivatives useful as inhibitors of enkephalinase and ace | MERRELL PHARMA INC (US) | 1997-12-29 | — | — | EP | claimed |
| EP-0481522-A1 | Novel mercaptoacetylamide derivatives useful as inhibitors of enkephalinase and ace | MERRELL PHARMACEUTICALS INC. (US) | 1992-04-22 | — | — | EP | claimed |
| US-4393072-A | Thienylbenzoic acid derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-07-12 | — | — | US | claimed |
| EP-0011282-B1 | THIENYLBENZOIC-ACID DERIVATIVES, PROCESS FOR THEIR PRODUCTION, AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE COMPOUNDS | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-02-16 | — | — | EP | claimed |
| US-12378254-B2 | Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators | JANSSEN PHARMACEUTICA NV (BE) | 2025-08-05 | — | — | US | disclosed |
| EP-4475828-A1 | METHODS FOR MONITORING PATIENT RESPONSE TO TREATMENT OF RETINAL OXIDATIVE DISEASES | Biojiva LLC (US) | 2024-12-18 | — | — | EP | disclosed |
| CN-118994095-A | Small molecule inhibitor and preparation method and application thereof | 上海医药工业研究院有限公司 | 2024-11-22 | — | — | CN | disclosed |
| US-4137391-A | Continuous solution polymerization of a conjugated diene with a monovinylaromatic compound using alkoxysilicon treating agents in the first reactor means of a reactor series | PHILLIPS PETROLEUM COMPANY (US) | 1979-01-30 | — | — | US | disclosed |
| US-4117017-A | PROCESS FOR PREPARATION OF THIOLS USING A BENZOPINACOL INITIATOR | W. R. GRACE & CO. (US) | 1978-09-26 | — | — | US | disclosed |
| US-4070361-A | Mercaptoalkylsulfonyl proline and pipecolic acid and esters thereof | E. R. SQUIBB & SONS, INC. (US) | 1978-01-24 | — | — | US | disclosed |
| US-3994920-A | APPETITE SUPPRESSANT, ANTIDEPRESSANT | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12378254-B2 | Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators | HCRTR2, HCRTR1, OXTR | ALOX15 719/4885LMNA 4524/4885KDM4E 454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.