Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | KCNJ1 | P48048 | 7/20 | 0.51 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8327061 | 0.85 | ALDH1A1 (0.49) | ALDH1A1NPSR1KCNJ1NOTUMNPC1 | |
| SCHEMBL18367780 | 0.83 | ALDH1A1 (0.47) | ALDH1A1NPSR1KCNJ1NOTUMNPC1 | |
| SCHEMBL12615992 | 0.80 | ALDH1A1 (0.68) | ALDH1A1NPSR1KCNJ1NOTUMNPC1 | |
| SCHEMBL478641 | 0.77 | NOTUM (0.49) | KCNJ1NOTUMTDP1 | |
| SCHEMBL29927629 | 0.77 | NOTUM (0.49) | KCNJ1NOTUMTDP1 | |
| SCHEMBL2854803 | 0.75 | NOTUM (0.42) | ALDH1A1NOTUMKMT2AMEN1LMNA | |
| SCHEMBL14232836 | 0.75 | ALDH1A1 (0.49) | ALDH1A1NPSR1KCNJ1NOTUMNPC1 | |
| SCHEMBL29935825 | 0.73 | LMNA (0.48) | ALDH1A1KMT2AKDM4EMEN1LMNA | |
| SCHEMBL16144650 | 0.73 | ALDH1A1 (0.54) | ALDH1A1NPSR1NOTUMNPC1KMT2A | |
| SCHEMBL8109135 | 0.72 | ALDH1A1 (0.58) | ALDH1A1NPSR1NOTUMNPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2152664-B1 | DIPEPTIDE ANALOGS AS COAGULATION FACTOR INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2014-09-03 | — | — | EP | disclosed |
| US-8367709-B2 | Dipeptide analogs as coagulation factor inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-02-05 | — | — | US | disclosed |
| US-20100173899-A1 | DIPEPTIDE ANALOGS AS COAGULATION FACTOR INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2010-07-08 | — | — | US | disclosed |
| WO-2008157162-A1 | DIPEPTIDE ANALOGS AS COAGULATION FACTOR INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-12-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100173899-A1 | DIPEPTIDE ANALOGS AS COAGULATION FACTOR INHIBITORS | F11, TFPI, SERPINC1 | ALDH1A1 4454/4885NPSR1 1815/4885KCNJ1 3864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.