SCHEMBL8113121

SCHEMBL8113121

O=S(=O)(Nc1cc(Br)c(O)cc1Br)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 6/20 0.56
GFER P55789 1/20 0.56
APOBEC3G Q9HC16 1/20 0.56
ERBB2 P04626 1/20 0.55
HSP90AA1 P07900 1/20 0.55
HSP90AB1 P08238 1/20 0.55
HTT P42858 3/20 0.53
ALDH1A1 P00352 3/20 0.53
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
MAPT P10636 1/20 0.50
MAPK1 P28482 1/20 0.50
RECQL P46063 1/20 0.50
HSD17B10 Q99714 3/20 0.49
ALOX15 P16050 2/20 0.48
HPGD P15428 1/20 0.48
CYTH2 Q99418 2/20 0.47
PGAM1 P18669 1/20 0.47
TSHR P16473 1/20 0.47
CA12 O43570 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7697271 0.79 GAA (0.51) GAAGFERAPOBEC3GERBB2HSP90AA1
SCHEMBL10611946 0.77 SLC40A1 (0.51) GAAGFERAPOBEC3GERBB2HSP90AA1
SCHEMBL10610753 0.76 MAPT (0.60) HTTALDH1A1MEN1KMT2AMAPT
SCHEMBL752345 0.75 GAA (0.80) GAAGFERAPOBEC3GERBB2HSP90AA1
SCHEMBL5731180 0.75 ALDH1A1 (0.58) GAAHTTALDH1A1MEN1KMT2A
SCHEMBL6662688 0.74 KEAP1 (0.57) MEN1KMT2ATSHRCA1CA2
SCHEMBL6549556 0.74 GAA (0.53) GAAGFERAPOBEC3GERBB2HSP90AA1
SCHEMBL2766342 0.74 METAP2 (0.64) GAAHTTALDH1A1MEN1KMT2A
SCHEMBL7590886 0.73 MEN1 (0.61) GAAHTTMEN1KMT2AMAPT
SCHEMBL6295404 0.73 GAA (0.64) GAAGFERAPOBEC3GERBB2HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6103351-A SUBSTRATE HAVING THEREON A THERMALLY SENSITIVE IMAGE-FORMING COMPOSITION COMPRISING AN ORGANIC SILVER SALT OXIDIZING AGENT AND A REDUCING AGENT FOR THE SALT WHICH COMPOSITION EXHIBITS VISUAL CHANGE IN RESPONSE TO THERMAL EXPOSURE EASTMAN KODAK COMPANY (US) 2000-08-15 US disclosed