SCHEMBL7697271

SCHEMBL7697271

O=S(=O)(Nc1cc(Br)c(O)c(Br)c1Br)c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.51
GFER P55789 1/20 0.51
APOBEC3G Q9HC16 1/20 0.51
ALOX15 P16050 2/20 0.50
HSD17B10 Q99714 2/20 0.50
ALDH1A1 P00352 2/20 0.50
MEN1 O00255 1/20 0.50
HPGD P15428 1/20 0.50
KMT2A Q03164 1/20 0.50
ERBB2 P04626 1/20 0.50
HSP90AA1 P07900 1/20 0.50
HSP90AB1 P08238 1/20 0.50
PGAM1 P18669 1/20 0.49
TSHR P16473 1/20 0.49
CYTH2 Q99418 2/20 0.49
HTT P42858 1/20 0.48
EP300 Q09472 1/20 0.47
BRAF P15056 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7696119 0.86 ALDH1A1 (0.56) GAAGFERALDH1A1MEN1KMT2A
SCHEMBL6549556 0.83 GAA (0.53) GAAGFERAPOBEC3GALOX15HSD17B10
SCHEMBL8113121 0.79 GAA (0.56) GAAGFERAPOBEC3GALOX15HSD17B10
SCHEMBL6209208 0.79 CYTH2 (0.66) GAAGFERAPOBEC3GALOX15HSD17B10
SCHEMBL5731180 0.74 ALDH1A1 (0.58) GAAALDH1A1MEN1KMT2AHTT
SCHEMBL6801689 0.74 RECQL (0.62) GAAGFERAPOBEC3GALOX15HSD17B10
SCHEMBL5309797 0.73 EP300 (0.68) MEN1KMT2AERBB2HSP90AA1HSP90AB1
SCHEMBL8113123 0.72 CYTH2 (0.54) GAAALOX15HSD17B10ALDH1A1MEN1
SCHEMBL7590886 0.72 MEN1 (0.61) GAAMEN1KMT2APGAM1TSHR
SCHEMBL10611946 0.72 SLC40A1 (0.51) GAAGFERAPOBEC3GALDH1A1ERBB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6380146-B1 FOR BLEACHING STAINS ON FABRICS DURING WASHING, WITHOUT PROVOKING DYE DAMAGE UNILEVER HOME & PERSONAL CARE USA A DIVISION OF CONOPCO, INC. 2002-04-30 US claimed
EP-1187899-A1 METHOD AND COMPOSITION FOR ENHANCING THE ACTIVITY OF AN ENZYME UNILEVER N.V. (NL) 2002-03-20 EP claimed
WO-2001000769-A1 METHOD AND COMPOSITION FOR ENHANCING THE ACTIVITY OF AN ENZYME UNILEVER N.V. (NL) 2001-01-04 WO claimed
WO-2001000768-A1 BLEACHING DETERGENT COMPOSITIONS UNILEVER N.V. (NL) 2001-01-04 WO claimed
US-6380146-B1 FOR BLEACHING STAINS ON FABRICS DURING WASHING, WITHOUT PROVOKING DYE DAMAGE UNILEVER HOME & PERSONAL CARE USA A DIVISION OF CONOPCO, INC. 2002-04-30 US disclosed
EP-1187899-A1 METHOD AND COMPOSITION FOR ENHANCING THE ACTIVITY OF AN ENZYME UNILEVER N.V. (NL) 2002-03-20 EP disclosed
US-6323014-B1 USED FOR REMOVING COLOURED STAINS FROM FABRICS BY WASHING UNILEVER HOME & PERSONAL CARE DIVISION OF CONOPCO, INC. 2001-11-27 US disclosed
WO-2001000769-A1 METHOD AND COMPOSITION FOR ENHANCING THE ACTIVITY OF AN ENZYME UNILEVER N.V. (NL) 2001-01-04 WO disclosed
WO-2001000768-A1 BLEACHING DETERGENT COMPOSITIONS UNILEVER N.V. (NL) 2001-01-04 WO disclosed