Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | NEK2 | P51955 | 2/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6996806 | 0.88 | ALDH1A1 (0.53) | ALDH1A1MAPTATMRXFP1ALOX5 | |
| SCHEMBL7001031 | 0.87 | LMNA (0.34) | ALOX5 | |
| SCHEMBL6999811 | 0.81 | ATM (0.47) | ALDH1A1MAPTATMRXFP1ALOX5 | |
| SCHEMBL7002378 | 0.74 | PKM (0.47) | ALDH1A1MAPTALOX5KDM4ESMN1; SMN2 | |
| SCHEMBL6996657 | 0.73 | SLC6A4 (0.35) | — | |
| SCHEMBL6996551 | 0.71 | ALDH1A1 (0.45) | ALDH1A1MAPTRXFP1ALOX5KDM4E | |
| SCHEMBL1928583 | 0.67 | ALOX5 (0.68) | ALDH1A1MAPTALOX5KDM4EHTR7 | |
| SCHEMBL5670589 | 0.64 | AHR (0.39) | ALDH1A1MAPTSMN1; SMN2HTR7HTR2B | |
| Hydrochloric Acid SCHEMBL5672533 | 0.63 | AHR (0.38) | MAPTSMN1; SMN2HTR7HTR2BALOX15 | |
| SCHEMBL7710980 | 0.63 | ALDH1A1 (0.52) | ALDH1A1MAPTATMRXFP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015437-A1 | BENZOXAZINE AND BENZOTHIAZINE DERIVATIVES AND THEIR USE IN PHARMACEUTICALS | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-07-05 | — | — | EP | disclosed |
| WO-1999012915-A1 | BENZOXAZINE AND BENZOTHIAZINE DERIVATIVES AND THEIR USE IN PHARMACEUTICALS | SCHERING AKTIENGESELLSCHAFT (DE) | 1999-03-18 | — | — | WO | disclosed |