SCHEMBL811407

SCHEMBL811407

CC(C)(C)C1(C(C)(C)C)C=CNC(c2ccccn2)=C1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.38
LMNA P02545 3/20 0.38
METAP1 P53582 3/20 0.38
CCR1 P32246 2/20 0.38
CCR5 P51681 2/20 0.38
CCR8 P51685 2/20 0.38
CYP1A2 P05177 1/20 0.38
POLB P06746 1/20 0.38
BLM P54132 1/20 0.38
HIF1A Q16665 1/20 0.38
DOHH Q9BU89 1/20 0.38
P4HTM Q9NXG6 1/20 0.38
NPC1 O15118 6/20 0.35
RAB9A P51151 5/20 0.35
TP53 P04637 3/20 0.34
HTT P42858 3/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
TDP1 Q9NUW8 2/20 0.34
ALOX15 P16050 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL820253 0.85 KDM4E (0.38) KDM4ELMNAMETAP1CCR1CCR5
SCHEMBL435395 0.80 KDM4E (0.42) KDM4ELMNAMETAP1CCR1CCR5
SCHEMBL1311500 0.77 KDM4E (0.39) KDM4ELMNAMETAP1CCR1CCR5
SCHEMBL7589588 0.76 KDM4E (0.42) KDM4ELMNAMETAP1CCR1CCR5
SCHEMBL15641196 0.76 KDM4E (0.42) KDM4ELMNAMETAP1CCR1CCR5
SCHEMBL1312502 0.76 KDM4E (0.38) KDM4ELMNAMETAP1CCR1CCR5
SCHEMBL9132747 0.75 KDM4E (0.37) KDM4ELMNAMETAP1CCR1CCR5
SCHEMBL6883837 0.74 KDM4E (0.39) KDM4ELMNAMETAP1CCR1CCR5
SCHEMBL7123291 0.74 KDM4E (0.36) KDM4ELMNAMETAP1CCR1CCR5
SCHEMBL7054134 0.73 KDM4E (0.38) KDM4ELMNAMETAP1CCR1CCR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4693687-A1 SEPARATOR OF LITHIUM-ION BATTERY, AND PREPARATION METHOD THEREFOR AND USE THEREOF SVOLT Energy Technology Co., Ltd. (CN) 2026-02-11 EP claimed
WO-2024217474-A1 SEPARATOR OF LITHIUM-ION BATTERY, AND PREPARATION METHOD THEREFOR AND USE THEREOF 蜂巢能源科技股份有限公司 2024-10-24 WO claimed
CN-118006052-A Environment-friendly flame-retardant polystyrene composite material and preparation method thereof 连云港传奇阻燃科技有限公司 2024-05-10 CN claimed
CN-117531371-B Microfiltration membrane of MABR membrane element and preparation method thereof 中源晟朝有限公司 2024-04-12 CN claimed
CN-117531371-A Microfiltration membrane of MABR membrane element and preparation method thereof 中源晟朝有限公司 2024-02-09 CN claimed
CN-116874745-A Thiophene derivative conjugated polymer containing amphoteric ions and preparation method and application thereof 浙江工业大学 2023-10-13 CN claimed
CN-115490582-B Preparation method of fluorine-containing biphenyl alkene negative monomer liquid crystal compound 烟台德润液晶材料有限公司 2023-10-10 CN claimed
CN-115490582-A Preparation method of fluorine-containing biphenyl alkene negative monomer liquid crystal compound 烟台德润液晶材料有限公司 2022-12-20 CN claimed
US-7709654-B2 Process for producing oxazole, imidazole, pyrrazole boryl compounds BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2010-05-04 US claimed
EP-4693687-A1 SEPARATOR OF LITHIUM-ION BATTERY, AND PREPARATION METHOD THEREFOR AND USE THEREOF SVOLT Energy Technology Co., Ltd. (CN) 2026-02-11 EP disclosed
US-12478621-B2 Substituted aminoquinolones as dgkalpha inhibitors for immune activation DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) 2025-11-25 US disclosed
EP-4605393-A1 TRIAZOLE-SUBSTITUTED IMIDAZO[1,2-A]PYRIMIDINES AS CGAS INHIBITORS GlaxoSmithKline Intellectual Property Development Limited (GB) 2025-08-27 EP disclosed
US-20250197381-A1 SUBSTITUTED TETRAHYDROFURANS AS MODULATORS OF SODIUM CHANNELS VERTEX PHARMACEUTICALS INCORPORATED (US) 2025-06-19 US disclosed
US-12331021-B2 Total synthesis of pirfenidone Suzhou Fude Zhaofeng Biochemical Technology Co., Ltd (CN) 2025-06-17 US disclosed
US-20160046597-A1 RORC2 INHIBITORS AND METHODS OF USE THEREOF PFIZER (US) 2016-02-18 US disclosed
EP-2390241-B1 METHOD FOR MANUFACTURING CONJUGATED AROMATIC COMPOUND SUMITOMO CHEMICAL CO (JP) 2014-10-01 EP disclosed
US-8598349-B2 Method for manufacturing conjugated aromatic compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-12-03 US disclosed
EP-2390241-A1 METHOD FOR MANUFACTURING CONJUGATED AROMATIC COMPOUND Sumitomo Chemical Company, Limited (JP) 2011-11-30 EP disclosed
US-20110275859-A1 METHOD FOR MANUFACTURING CONJUGATED AROMATIC COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED 2011-11-10 US disclosed
US-20110256790-A1 THERMAL INSULATION CONTAINING SUPPLEMENTAL INFRARED RADIATION ABSORBING MATERIAL SAINT-GOBAIN ISOVER (FR) 2011-10-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110275859-A1 METHOD FOR MANUFACTURING CONJUGATED AROMATIC COMPOUND C9, H1-10, CYP1A1 KDM4E 724/4885LMNA 1269/4885METAP1 2979/4885
US-20160046597-A1 RORC2 INHIBITORS AND METHODS OF USE THEREOF RORC, RORB, RORA KDM4E 1807/4885LMNA 3310/4885METAP1 2936/4885
US-12478621-B2 Substituted aminoquinolones as dgkalpha inhibitors for immune activation DGKK, DGKG, DGKA KDM4E 1315/4885LMNA 1953/4885METAP1 3401/4885
US-12331021-B2 Total synthesis of pirfenidone PIR, CYP2B6, CYP26B1 KDM4E 386/4885LMNA 4815/4885METAP1 553/4885
US-20250197381-A1 SUBSTITUTED TETRAHYDROFURANS AS MODULATORS OF SODIUM CHANNELS TRPV1, TRPA1, SCN2B KDM4E 2978/4885LMNA 3179/4885METAP1 4157/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.