Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8870829 | 0.99 | TLR8 (0.35) | TLR8MAOASIGMAR1CYP1A2CYP2D6 | |
| SCHEMBL8114240 | 0.90 | KDM4E (0.37) | CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL8871802 | 0.88 | LMNA (0.38) | CYP1A2CYP2D6 | |
| SCHEMBL9684037 | 0.87 | S1PR1 (0.38) | SIGMAR1HTR2A | |
| SCHEMBL9437775 | 0.86 | SIGMAR1 (0.36) | SIGMAR1CYP1A2CYP2D6 | |
| SCHEMBL9684946 | 0.86 | BCHE (0.37) | — | |
| SCHEMBL9437752 | 0.86 | THRA (0.31) | — | |
| SCHEMBL9685609 | 0.85 | DRD2 (0.39) | SIGMAR1CYP1A2CYP2D6CYP2C19HTR2A | |
| SCHEMBL9437753 | 0.84 | SIGMAR1 (0.39) | SIGMAR1CYP1A2CYP2D6 | |
| SCHEMBL7760492 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673933-B1 | Aminoalkyl benzoxazolinones and benzothiazolinones process for their preparation and compositions containing them | ADIR (FR) | 2000-11-08 | — | — | EP | disclosed |
| US-5534511-A | AFFINITY FOR SIGMA RECEPTORS, ANTIINFLAMMATORY, TREATMENT OF ARTHRITIS | ADIR ET COMPAGNIE (FR) | 1996-07-09 | — | — | US | disclosed |
| EP-0673933-A1 | Aminoalkyl benzoxazolinones and benzothiazolinones process for their preparation and compositions containing them | ADIR ET COMPAGNIE (FR) | 1995-09-27 | — | — | EP | disclosed |
| US-5296477-A | Antidepressants | ADIR ET COMPAGNIE (FR) | 1994-03-22 | — | — | US | disclosed |
| US-5268381-A | Antidepressant or anxiolytic compound | ADIR ET COMPAGNIE (FR) | 1993-12-07 | — | — | US | disclosed |
| US-5196434-A | Antidepressants, anxiolytic agents | ADIR ET COMPAGNIE (FR) | 1993-03-23 | — | — | US | disclosed |
| EP-0478446-A1 | Heterocyclic alkylamines, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-04-01 | — | — | EP | disclosed |