Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7760492 | 0.96 | — | — | |
| SCHEMBL9684037 | 0.87 | S1PR1 (0.38) | THRATHRBS1PR1 | |
| SCHEMBL8109894 | 0.86 | SIGMAR1 (0.40) | — | |
| SCHEMBL8114166 | 0.86 | TLR8 (0.36) | — | |
| SCHEMBL9684946 | 0.86 | BCHE (0.37) | S1PR1 | |
| SCHEMBL9685609 | 0.85 | DRD2 (0.39) | THRATHRBS1PR1 | |
| Hydrochloric Acid SCHEMBL8870829 | 0.84 | TLR8 (0.35) | — | |
| SCHEMBL8109680 | 0.83 | L3MBTL1 (0.41) | — | |
| SCHEMBL7766397 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL8871371 | 0.82 | L3MBTL1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5296477-A | Antidepressants | ADIR ET COMPAGNIE (FR) | 1994-03-22 | — | — | US | disclosed |
| US-5268381-A | Antidepressant or anxiolytic compound | ADIR ET COMPAGNIE (FR) | 1993-12-07 | — | — | US | disclosed |
| US-5196434-A | Antidepressants, anxiolytic agents | ADIR ET COMPAGNIE (FR) | 1993-03-23 | — | — | US | disclosed |
| EP-0478446-A1 | Heterocyclic alkylamines, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-04-01 | — | — | EP | disclosed |
| US-5084469-A | Analgesics | ADIR ET COMPAGNIE (FR) | 1992-01-28 | — | — | US | disclosed |