Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 6/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.40 |
| ▸ | ADAM10 | O14672 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | ADAM8 | P78325 | 2/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | BMP1 | P13497 | 1/20 | 0.37 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.37 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.36 |
| ▸ | CCR10 | P46092 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8112071 | 0.92 | MMP2 (0.39) | ADAM17ADAM10MMP2MMP9ADAM8 | |
| SCHEMBL8121501 | 0.86 | NPY1R (0.45) | NPY1RADAM17ADAM10MMP2MMP9 | |
| SCHEMBL8115000 | 0.84 | RAB9A (0.43) | MMP2MMP9MMP12MMP14CCR10 | |
| SCHEMBL8114996 | 0.84 | RAB9A (0.43) | MMP2MMP9MMP12MMP14CCR10 | |
| SCHEMBL8127300 | 0.80 | NPY1R (0.47) | NPY1RNPFFR1NPFFR2NPY5R | |
| SCHEMBL8121201 | 0.79 | NPY1R (0.54) | NPY1RNPFFR1NPFFR2NPY5RCA1 | |
| SCHEMBL8119000 | 0.78 | PSEN1 (0.39) | MMP2MMP9BMP1MMP1 | |
| SCHEMBL8128197 | 0.78 | MMP2 (0.40) | ADAM17ADAM10MMP2MMP9ADAM8 | |
| SCHEMBL8119387 | 0.77 | NPY1R (0.45) | NPY1RMMP2NPFFR1NPFFR2NPY5R | |
| SCHEMBL8123411 | 0.77 | NPY1R (0.57) | NPY1RNPFFR1NPFFR2NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |