Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.40 |
| ▸ | ADAM10 | O14672 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.40 |
| ▸ | ADAM8 | P78325 | 2/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | CCR10 | P46092 | 5/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 4/20 | 0.38 |
| ▸ | TMPRSS6 | Q8IU80 | 4/20 | 0.38 |
| ▸ | BMP1 | P13497 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8112071 | 0.85 | MMP2 (0.39) | MMP2ADAM10MMP9ADAM8ADAM17 | |
| SCHEMBL8118999 | 0.78 | NPY1R (0.42) | MMP2ADAM10MMP9ADAM8ADAM17 | |
| SCHEMBL1388417 | 0.77 | PADI6 (0.44) | — | |
| SCHEMBL4650700 | 0.77 | NPY1R (0.55) | — | |
| SCHEMBL1388294 | 0.77 | TACR1 (0.46) | — | |
| SCHEMBL7751919 | 0.74 | MCHR1 (0.53) | — | |
| SCHEMBL9196942 | 0.73 | NPY4R (0.33) | CCR10 | |
| SCHEMBL8123073 | 0.71 | PSEN1 (0.38) | BMP1 | |
| SCHEMBL1388993 | 0.71 | HSD11B1 (0.37) | — | |
| SCHEMBL8115000 | 0.71 | RAB9A (0.43) | MMP2MMP9MMP12MMP14CCR10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |