Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 12/20 | 0.40 |
| ▸ | MMP9 | P14780 | 11/20 | 0.40 |
| ▸ | CCR10 | P46092 | 5/20 | 0.39 |
| ▸ | MMP7 | P09237 | 3/20 | 0.39 |
| ▸ | MMP1 | P03956 | 2/20 | 0.39 |
| ▸ | MMP3 | P08254 | 2/20 | 0.39 |
| ▸ | MMP13 | P45452 | 2/20 | 0.39 |
| ▸ | MMP8 | P22894 | 4/20 | 0.38 |
| ▸ | MMP12 | P39900 | 4/20 | 0.38 |
| ▸ | MMP14 | P50281 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8115000 | 1.00 | RAB9A (0.43) | RAB9AITGB3ITGA2BMMP2MMP9 | |
| SCHEMBL8112071 | 0.88 | MMP2 (0.39) | ITGB3ITGA2BMMP2MMP9CCR10 | |
| SCHEMBL8118999 | 0.84 | NPY1R (0.42) | MMP2MMP9CCR10MMP1MMP12 | |
| SCHEMBL8126524 | 0.83 | MC4R (0.35) | RAB9A | |
| SCHEMBL8126529 | 0.83 | MC4R (0.35) | RAB9A | |
| SCHEMBL8112361 | 0.78 | MC4R (0.34) | — | |
| SCHEMBL8112073 | 0.76 | PSEN1 (0.36) | CCR10 | |
| SCHEMBL8112352 | 0.73 | NOS1 (0.40) | MMP2 | |
| SCHEMBL1799131 | 0.72 | BMP1 (0.54) | MMP2MMP9MMP7MMP1MMP3 | |
| SCHEMBL8119000 | 0.72 | PSEN1 (0.39) | MMP2MMP9MMP1MMP13MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |
| EP-0680469-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | Dr. Karl Thomae GmbH (DE) | 1995-11-08 | — | — | EP | disclosed |
| WO-1994017035-A1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1994-08-04 | — | — | WO | disclosed |