Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 10/20 | 0.38 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8123768 | 0.92 | PPARA (0.41) | KAT8PPARAFBP1PLCG2ALDH1A1 | |
| SCHEMBL8118480 | 0.85 | PTPRB (0.42) | PKMKAT8PPARARAB9AMEN1 | |
| SCHEMBL8124637 | 0.83 | RAB9A (0.44) | PKMSMN1; SMN2NPSR1RAB9AMEN1 | |
| SCHEMBL8118990 | 0.82 | KAT8 (0.47) | KAT8PPARASMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL8124732 | 0.82 | FBP1 (0.46) | PKMFBP1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL8125598 | 0.82 | PTPN1 (0.48) | FBP1SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL8119109 | 0.81 | ALOX15 (0.41) | PKMKAT8FBP1SMN1; SMN2RAB9A | |
| SCHEMBL8109251 | 0.81 | KAT8 (0.38) | PKMKAT8PPARAFBP1SMN1; SMN2 | |
| SCHEMBL8124141 | 0.80 | RAB9A (0.39) | PKMKAT8PPARAFBP1SMN1; SMN2 | |
| SCHEMBL8124759 | 0.80 | KAT8 (0.39) | PKMKAT8PPARASMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036069-A1 | BENZENESULFONAMIDE COMPOUNDS | PHARMACIA & UPJOHN S.p.A. (IT) | 2000-09-20 | — | — | EP | disclosed |
| WO-1999028306-A1 | BENZENESULFONAMIDE COMPOUNDS | PHARMACIA & UPJOHN S.P.A. (IT) | 1999-06-10 | — | — | WO | disclosed |