Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 14/20 | 0.52 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5292521 | 0.97 | KIF11 (0.54) | KIF11KCNN4CYP11B1CYP11B2KCNH2 | |
| Iodide SCHEMBL5085031 | 0.95 | KIF11 (0.52) | KIF11KCNN4CYP11B1CYP11B2KCNH2 | |
| Hydrochloric Acid SCHEMBL5092615 | 0.95 | KIF11 (0.52) | KIF11KCNN4CYP11B1CYP11B2KCNH2 | |
| Bromide SCHEMBL1568274 | 0.86 | KIF11 (0.59) | KIF11CYP11B1CYP11B2KCNH2CYP3A4 | |
| Bromide SCHEMBL28967851 | 0.84 | KIF11 (0.57) | KIF11CYP11B1CYP11B2KCNH2CYP3A4 | |
| SCHEMBL1127900 | 0.83 | KIF11 (0.61) | KIF11CYP11B1CYP11B2KCNH2CYP3A4 | |
| Bromide SCHEMBL3785728 | 0.82 | KIF11 (0.55) | KIF11CYP11B1CYP11B2KCNH2CYP3A4 | |
| Bromide SCHEMBL5092309 | 0.82 | KIF11 (0.55) | KIF11CYP11B1CYP11B2KCNH2CYP3A4 | |
| Bromide SCHEMBL678763 | 0.82 | KIF11 (0.55) | KIF11CYP11B1CYP11B2KCNH2CYP3A4 | |
| Bromide SCHEMBL10797449 | 0.82 | KIF11 (0.55) | KIF11CYP11B1CYP11B2KCNH2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119978028-A | Preparation method of high-temperature-resistant phosphorus salt antistatic agent | 达创新材料科技(山东)有限公司 | 2025-05-13 | — | — | CN | claimed |
| CN-112358497-A | Preparation method of polysulfide silane coupling agent with lighter color | 南京曙光精细化工有限公司 | 2021-02-12 | — | — | CN | claimed |
| CN-107353858-B | Packaging adhesive for infrared LED chip and preparation method and application thereof | 广州惠利电子材料有限公司 | 2020-11-10 | — | — | CN | claimed |
| CN-111234185-A | High-crystallinity bifunctional polyester resin for low-temperature curing extinction powder coating and synthesis method thereof | 浙江光华科技股份有限公司 | 2020-06-05 | — | — | CN | claimed |
| CN-111205618-A | Low-temperature impact-resistant high-transmittance flame-retardant polycarbonate composite material and preparation method thereof | 宁波坚锋新材料有限公司 | 2020-05-29 | — | — | CN | claimed |
| US-9522915-B2 | Method for preparing an important intermediate of linagliptin | 2Y-CHEM, LTD. (CN) | 2016-12-20 | — | — | US | claimed |
| US-20150274728-A1 | METHOD FOR PREPARING AN IMPORTANT INTERMEDIATE OF LINAGLIPTIN | 2Y-CHEM, LTD. (CN) | 2015-10-01 | — | — | US | claimed |
| EP-0764676-B1 | Method of preparing polycarbonate-polysiloxane block copolymers | GEN ELECTRIC (US) | 2004-04-28 | — | — | EP | claimed |
| EP-0010843-B1 | METHOD OF MAKING 5,6-DIHYDRO-2-METHYL-N-PHENYL-1,4-OXATHIIN-3-CARBOXAMIDE | UNIROYAL LTD. (CA) | 1983-11-09 | — | — | EP | claimed |
| US-4247707-A | CATALYTIC LIQUID-PHASE OXIDATION OF 2-METHYL-N-PHENYL-1,3-OXATHIOLANE-2-ACETAMIDE; THEN CATALYTIC THERMAL RING EXPANSION | UNIROYAL CHEMICAL CO./UNIROYAL CHEMICAL CLE. (CA) | 1981-01-27 | — | — | US | claimed |
| EP-0010843-A1 | Method of making 5,6-dihydro-2-methyl-N-phenyl-1,4-oxathiin-3-carboxamide | UNIROYAL LTD. (CA) | 1980-05-14 | — | — | EP | claimed |
| WO-2026087965-A1 | COMPOSITION COMPRISING EPOXY RESIN WITH CONSTRAINED AROMATIC RINGS AND PHOTOBASE | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2026-04-30 | — | — | WO | disclosed |
| US-12479781-B2 | Process for the preparation of ethylene glycol | SHELL USA, INC. (US) | 2025-11-25 | — | — | US | disclosed |
| US-12479856-B2 | Pharmaceutical compounds for the treatment of complement mediated disorders | ACHILLION PHARMACEUTICALS, INC. (US) | 2025-11-25 | — | — | US | disclosed |
| WO-2025200154-A1 | TWO-PART EPOXY COMPOSITION COMPRISING THIOL CURATIVE, AND CATALYST | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2025-10-02 | — | — | WO | disclosed |
| US-4554010-A | 5-Deoxy-3-O-arylmethyl or substituted arylmethyl-1,2-O-substituted-alkylidene-alpha-D-xylofuranose herbicide derivatives | CHEVRON RESEARCH COMPANY (US) | 1985-11-19 | — | — | US | disclosed |
| US-4515618-A | PLANT GROWTH REGULATORS | CHEVRON RESEARCH COMPANY (US) | 1985-05-07 | — | — | US | disclosed |
| US-4429119-A | PLANT GROWTH REGULATORS | CHEVRON RESEARCH COMPANY (US) | 1984-01-31 | — | — | US | disclosed |
| US-4247707-A | CATALYTIC LIQUID-PHASE OXIDATION OF 2-METHYL-N-PHENYL-1,3-OXATHIOLANE-2-ACETAMIDE; THEN CATALYTIC THERMAL RING EXPANSION | UNIROYAL CHEMICAL CO./UNIROYAL CHEMICAL CLE. (CA) | 1981-01-27 | — | — | US | disclosed |
| US-4160116-A | FROM THE CORRESPONDING OXIDE BY HYDRATION USING ORGANIC PHOSPHONIUM HALIDE CATALYST, CARBON DIOXIDE | SHOWA DENKO K.K. (JP) | 1979-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12479856-B2 | Pharmaceutical compounds for the treatment of complement mediated disorders | C5, CFH, C1QBP | KIF11 3145/4885KCNN4 3362/4885CYP11B1 1778/4885 |
| US-20150274728-A1 | METHOD FOR PREPARING AN IMPORTANT INTERMEDIATE OF LINAGLIPTIN | DPP4, DPP9, DPP3 | KIF11 2763/4885KCNN4 2399/4885CYP11B1 3197/4885 |
| US-12479781-B2 | Process for the preparation of ethylene glycol | GYS1, LIPG, LIPE | KIF11 3352/4885KCNN4 4423/4885CYP11B1 426/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.