Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | RXRB | P28702 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 2/20 | 0.38 |
| ▸ | RXRG | P48443 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7913287 | 0.86 | KDM4E (0.54) | RAB9AALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL7910337 | 0.77 | KDM4E (0.55) | RAB9ARXRBALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL9312600 | 0.67 | ALDH1A1 (0.43) | RAB9AALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL4050992 | 0.67 | RXRB (0.64) | RAB9ARXRBALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL2894580 | 0.66 | SLC9A1 (0.48) | RAB9AALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL7913282 | 0.66 | KDM4E (0.49) | RAB9AALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL7910295 | 0.65 | SLC9A1 (0.65) | RAB9AALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL2556246 | 0.65 | ALDH1A1 (0.54) | RAB9AALDH1A1SMN1; SMN2LMNATP53 | |
| SCHEMBL23090393 | 0.65 | KDM4E (0.47) | RAB9AALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL10471696 | 0.65 | KDM4E (0.46) | RAB9AALDH1A1SMN1; SMN2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972767-A1 | CYCLOALKA[b]PYRIDINE-3-CARBONYLGUANIDINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND DRUGS CONTAINING THE SAME | TOA EIYO LTD. (JP) | 2000-01-19 | — | — | EP | disclosed |