SCHEMBL81292

SCHEMBL81292

[N-]=[N+]=CC(=O)Oc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.48
CYP1A2 P05177 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
TDP1 Q9NUW8 2/20 0.42
ATM Q13315 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
ALOX15 P16050 2/20 0.41
HPGD P15428 1/20 0.41
HSD17B10 Q99714 1/20 0.41
MAOB P27338 1/20 0.40
KMT2A Q03164 3/20 0.40
RAD51 Q06609 1/20 0.40
MEN1 O00255 1/20 0.39
MAPT P10636 2/20 0.39
KDM4E B2RXH2 1/20 0.39
NSD2 O96028 1/20 0.39
HTR1A P08908 1/20 0.38
ELANE P08246 1/20 0.37
ALDH1A1 P00352 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14125424 0.80 LDHA (0.40) NPSR1L3MBTL1MAOBKMT2AMEN1
SCHEMBL28252455 0.78 CES2 (0.47) KMT2AMEN1MAPTKDM4EALDH1A1
SCHEMBL31162420 0.76 CYP1A2 (0.41) NPSR1CYP1A2CYP2C9CYP2C19HPGD
SCHEMBL356193 0.75 HPGD (0.57) TDP1ATML3MBTL1ALOX15HPGD
SCHEMBL1249384 0.75 HPGD (0.57) TDP1ATML3MBTL1ALOX15HPGD
SCHEMBL356194 0.75 HPGD (0.57) TDP1ATML3MBTL1ALOX15HPGD
SCHEMBL9398038 0.75 TDP1 (0.50) TDP1ATML3MBTL1ALOX15HPGD
SCHEMBL1271951 0.74 GAA (0.53) NPSR1HPGDKMT2AMEN1MAPT
SCHEMBL9725995 0.73 CYP1A2 (0.61) NPSR1CYP1A2CYP2C9CYP2C19L3MBTL1
SCHEMBL7516109 0.73 CYP19A1 (0.44) NPSR1CYP1A2CYP2C9CYP2C19TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 522 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12473688-B2 Carbene co-grafting modified fabric, preparation and application thereof SOOCHOW UNIVERSITY (CN) 2025-11-18 US claimed
US-20240344265-A1 CARBENE CO-GRAFTING MODIFIED FABRIC, PREPARATION AND APPLICATION THEREOF SOOCHOW UNIVERSITY (CN) 2024-10-17 US claimed
WO-2023155368-A1 CARBENE CO-GRAFTED MODIFIED FABRIC, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF 苏州大学 2023-08-24 WO claimed
CN-114481608-B Carbene co-grafting modified fabric and preparation method and application thereof 苏州大学 2022-12-30 CN claimed
CN-110092769-B Chromene derivative and synthesis method and application thereof 华东师范大学 2022-09-20 CN claimed
CN-114481608-A Carbene co-grafted modified fabric and preparation method and application thereof 苏州大学 2022-05-13 CN claimed
CN-106831764-B A kind of Indoli zine derivatives and preparation method thereof 苏州大学 2018-11-02 CN claimed
CN-106831764-A A kind of Indoli zine derivatives and preparation method thereof 苏州大学 2017-06-13 CN claimed
CN-105884647-A Synthesis method of 3-hydroxyl diazoester intermediate alkyne compound 湖北科技学院 2016-08-24 CN claimed
US-20160208114-A1 CONDUCTIVE POLYMERIC COATINGS, MEDICAL DEVICES, COATING SOLUTIONS AND METHODS HERAEUS MEDICAL COMPONENTS LLC 2016-07-21 US claimed
EP-3039087-A1 CONDUCTIVE POLYMERIC COATINGS, MEDICAL DEVICES, COATING SOLUTIONS AND METHODS SurModics, Inc. (US) 2016-07-06 EP claimed
WO-2015031265-A1 CONDUCTIVE POLYMERIC COATINGS, MEDICAL DEVICES, COATING SOLUTIONS AND METHODS SURMODICS, INC. (US) 2015-03-05 WO claimed
US-20030013696-A1 Methods and compositions for photo-cross linking photoactive compounds to target tissue BRITISH COLUMBIA, UNIVERSITY OF, THE (CA) 2003-01-16 US claimed
WO-2002076453-A1 METHODS AND COMPOSITIONS FOR PHOTO-CROSS LINKING PHOTOACTIVE COMPOUNDS TO TARGET TISSUE THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2002-10-03 WO claimed
CN-121974832-A Sulfonate synthesis method based on flow photochemistry technology 绍兴文理学院 2026-05-05 CN disclosed
US-12616777-B2 Silicone polyurea block copolymer coating compositions and methods INNOVATIVE SURFACE TECHNOLOGIES, INC. (US) 2026-05-05 US disclosed
US-20260108663-A1 LOW PARTICULATE LUBRICIOUS COATING WITH VINYL PYRROLIDONE AND ACIDIC POLYMER-CONTAINING LAYERS SURMODICS INC (US) 2026-04-23 US disclosed
US-5512474-A Cell culture support containing a cell adhesion factor and a positively-charged molecule BSI CORPORATION (US) 1996-04-30 US disclosed
WO-1991007485-A1 IMPROVED BIOREACTOR SURFACES AND METHODS OF MAKING SAME BIO-METRIC SYSTEMS, INC. (US) 1991-05-30 WO disclosed
US-5002582-A Natural or synthetic resins bonded through latent reactive groups BIO-METRIC SYSTEMS, INC. (US) 1991-03-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12616777-B2 Silicone polyurea block copolymer coating compositions and methods PGF, CASK, C9 NPSR1 2518/4885CYP1A2 2700/4885CYP2C9 2102/4885
US-20260108663-A1 LOW PARTICULATE LUBRICIOUS COATING WITH VINYL PYRROLIDONE AND ACIDIC POLYMER-CONTAINING LAYERS VCL, RAD54L, SELP NPSR1 3097/4885CYP1A2 966/4885CYP2C9 772/4885
US-20030013696-A1 Methods and compositions for photo-cross linking photoactive compounds to target tissue LCP1, PPOX, TYR NPSR1 2856/4885CYP1A2 1107/4885CYP2C9 1042/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.