Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7913304 | 0.85 | ACHE (0.42) | ALDH1A1MEN1KMT2ASLC9A1SMN1; SMN2 | |
| SCHEMBL7913113 | 0.79 | SLC9A1 (0.37) | ALDH1A1SLC9A1SMN1; SMN2LMNAMAPT | |
| Cadaverine Tartrate SCHEMBL7902842 | 0.76 | SLC9A1 (0.33) | SLC9A1 | |
| SCHEMBL7911292 | 0.73 | KDM4E (0.48) | ALDH1A1KMT2AMAPK1KDM4EHPGD | |
| SCHEMBL8132478 | 0.73 | SLC9A1 (0.62) | ALDH1A1MEN1KMT2ASLC9A1SMN1; SMN2 | |
| SCHEMBL7910295 | 0.72 | SLC9A1 (0.65) | ALDH1A1MEN1KMT2ASLC9A1SMN1; SMN2 | |
| SCHEMBL8143615 | 0.70 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2ASLC9A1SMN1; SMN2 | |
| SCHEMBL23394674 | 0.67 | — | — | |
| SCHEMBL17641587 | 0.67 | NPC1 (0.51) | ALDH1A1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL70795 | 0.67 | SMN1; SMN2 (0.65) | ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972767-A1 | CYCLOALKA[b]PYRIDINE-3-CARBONYLGUANIDINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND DRUGS CONTAINING THE SAME | TOA EIYO LTD. (JP) | 2000-01-19 | — | — | EP | disclosed |