Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7902974 | 0.87 | KDM4E (0.50) | ACHEGAAKDM4EKMT2ANPC1 | |
| SCHEMBL8136306 | 0.85 | ALDH1A1 (0.38) | KDM4EKMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL7913113 | 0.79 | SLC9A1 (0.37) | KDM4EALDH1A1LMNASLC9A1SMN1; SMN2 | |
| SCHEMBL7911292 | 0.78 | KDM4E (0.48) | ACHEGAAKDM4EKMT2ANPC1 | |
| SCHEMBL927885 | 0.74 | SLC9A1 (0.60) | ACHEGAAKDM4EKMT2ANPC1 | |
| Maleic Acid SCHEMBL7916784 | 0.74 | LMNA (0.33) | RAB9AALDH1A1LMNASLC9A1SMN1; SMN2 | |
| SCHEMBL7902989 | 0.72 | ACHE (0.46) | ACHEGAAKDM4EKMT2ANPC1 | |
| SCHEMBL7912975 | 0.72 | ACHE (0.46) | ACHEGAAKDM4EKMT2ANPC1 | |
| SCHEMBL7913218 | 0.70 | ACHE (0.42) | ACHEGAAKDM4EKMT2ANPC1 | |
| SCHEMBL7916322 | 0.70 | SLC9A1 (0.33) | KDM4ESLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6258829-B1 | ANTIARRTHMIA AGENTS AND CARDIOVASCULAR DISORDERS | TOA EIYO LTD. (JP) | 2001-07-10 | — | — | US | disclosed |
| EP-0972767-A1 | CYCLOALKA[b]PYRIDINE-3-CARBONYLGUANIDINE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND DRUGS CONTAINING THE SAME | TOA EIYO LTD. (JP) | 2000-01-19 | — | — | EP | disclosed |