Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8135408 | 0.88 | ROCK2 (0.51) | ROCK2RAB9AALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL8134584 | 0.87 | ROCK2 (0.50) | ROCK2RAB9AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL8129497 | 0.85 | ALDH1A1 (0.53) | ROCK2RAB9AALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL7096106 | 0.83 | ROCK2 (0.59) | ROCK2RAB9AKMT2AGAASLC6A2 | |
| SCHEMBL8138188 | 0.83 | LNPEP (0.57) | ROCK2RAB9ACYP1A2ALDH1A1SMN1; SMN2 | |
| SCHEMBL8135411 | 0.81 | RAB9A (0.63) | ROCK2RAB9AALDH1A1KMT2AMAPK1 | |
| SCHEMBL8133659 | 0.78 | ROCK2 (0.59) | ROCK2RAB9ALMNAKMT2ASLC6A2 | |
| SCHEMBL9054261 | 0.77 | MAPT (0.57) | RAB9ACYP1A2ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL8122588 | 0.77 | ROCK2 (0.57) | ROCK2RAB9AMAPT | |
| SCHEMBL8130076 | 0.75 | ROCK2 (0.51) | ROCK2RAB9ACYP1A2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0720601-B1 | GASTRIN AND CCK RECEPTOR LIGANDS | BLACK JAMES FOUNDATION (GB) | 2000-10-25 | — | — | EP | disclosed |
| US-5919829-A | Gastrin and cck receptor ligands | JAMES BLACK FOUNDATION LIMITED (GB) | 1999-07-06 | — | — | US | disclosed |
| US-5795907-A | Gastin and CCK receptor ligands | JAMES BLACK FOUNDATION LIMITED (GB) | 1998-08-18 | — | — | US | disclosed |