Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 4/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.35 |
| ▸ | MAP3K5 | Q99683 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.31 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14878375 | 0.83 | GABRA5 (0.39) | GABRA5GABRG2GABRB3MAP3K5GABRA1 | |
| SCHEMBL12691838 | 0.79 | GABRA5 (0.41) | GABRA5GABRG2GABRB3MAP3K5GABRA1 | |
| SCHEMBL3959344 | 0.78 | GABRG2 (0.44) | GABRA5GABRG2GABRB3MAP3K5GABRA1 | |
| SCHEMBL8122644 | 0.75 | LMNA (0.37) | MAPTGAASMN1; SMN2LMNAKDM4E | |
| SCHEMBL20085591 | 0.73 | MAPT (0.33) | CYP11B2MAPTGAASMN1; SMN2LMNA | |
| SCHEMBL8125926 | 0.70 | F10 (0.41) | MAPTGAASMN1; SMN2LMNAKDM4E | |
| SCHEMBL31481226 | 0.67 | CYP11B2 (0.53) | GABRA5GABRG2GABRB3GABRA1CYP11B1 | |
| SCHEMBL520359 | 0.67 | CYP11B2 (0.53) | GABRA5GABRG2GABRB3GABRA1CYP11B1 | |
| SCHEMBL14980087 | 0.67 | CYP19A1 (0.38) | GABRA5GABRG2GABRB3CYP11B1CYP11B2 | |
| SCHEMBL14878379 | 0.67 | MAP3K5 (0.31) | GABRA5GABRG2GABRB3MAP3K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054889-A1 | NEW OXAZOLIDINONES WITH AZOL-CONTAINING TRICYCLES | Bayer Aktiengesellschaft (DE) | 2000-11-29 | — | — | EP | disclosed |
| WO-1999040094-A1 | AGENT FOR SEALING METALLIC GROUND COATS, ESPECIALLY GROUND COATS CONSISTING OF ZINC OR ZINC ALLOYS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-08-12 | — | — | WO | disclosed |