Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 7/20 | 0.43 |
| ▸ | GABRP | O00591 | 6/20 | 0.43 |
| ▸ | GABRD | O14764 | 6/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 6/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 6/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 6/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 6/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 6/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 6/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 6/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 6/20 | 0.43 |
| ▸ | GABRE | P78334 | 6/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 6/20 | 0.43 |
| ▸ | GABRG1 | Q8N1C3 | 6/20 | 0.43 |
| ▸ | GABRG3 | Q99928 | 6/20 | 0.43 |
| ▸ | GABRQ | Q9UN88 | 6/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5278269 | 0.78 | AVPR1A (0.38) | OPRK1PDE4DALDH1A1RIPK1 | |
| SCHEMBL16601607 | 0.78 | GABRG2 (0.35) | GRM5GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL8182091 | 0.78 | BLM (0.51) | GABRG2GABRB3GABRA5THRBMAPT | |
| Hydrochloric Acid SCHEMBL5277480 | 0.77 | AVPR1A (0.38) | OPRK1PDE4DALDH1A1RIPK1 | |
| SCHEMBL9851802 | 0.73 | CYP11B2 (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL432928 | 0.72 | GRM5 (0.43) | GRM5GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL11778334 | 0.71 | CYP11B2 (0.54) | HSD17B3OPRK1PDE4DLMNAALDH1A1 | |
| SCHEMBL10735133 | 0.70 | THRB (0.43) | GRM5GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL20904025 | 0.70 | AADAT (0.44) | GRM5GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL10729236 | 0.70 | THRB (0.43) | GRM5GABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054889-A1 | NEW OXAZOLIDINONES WITH AZOL-CONTAINING TRICYCLES | Bayer Aktiengesellschaft (DE) | 2000-11-29 | — | — | EP | disclosed |
| EP-1029854-A1 | Oxazolidinones and their use as antibacterial agents | BAYER AG (DE) | 2000-08-23 | — | — | EP | disclosed |
| WO-1999040094-A1 | AGENT FOR SEALING METALLIC GROUND COATS, ESPECIALLY GROUND COATS CONSISTING OF ZINC OR ZINC ALLOYS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-08-12 | — | — | WO | disclosed |