Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3323053 | 0.78 | ALDH1A1 (0.45) | — | |
| SCHEMBL8146861 | 0.78 | SLC1A2 (0.47) | — | |
| SCHEMBL3323051 | 0.78 | CYP3A4 (0.42) | KDM4EHSD17B10 | |
| SCHEMBL8146680 | 0.78 | THRB (0.55) | MTNR1A | |
| SCHEMBL8145351 | 0.75 | OGA (0.59) | KDM4EGAA | |
| SCHEMBL29504706 | 0.74 | MC4R (0.56) | KDM4EL3MBTL1 | |
| SCHEMBL210586 | 0.74 | CYP1A2 (0.46) | KDM4EL3MBTL1 | |
| SCHEMBL8154739 | 0.74 | KDM4E (0.55) | MTNR1AKDM4EGAAHSD17B10L3MBTL1 | |
| SCHEMBL8145105 | 0.73 | NPSR1 (0.47) | — | |
| SCHEMBL8136256 | 0.72 | NOS2 (0.57) | MTNR1AKDM4EGAAHSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008119741-A2 | 3-IMIDAZOLYL-INDOLES FOR THE TREATMENT OF PROLIFERATIVE DISEASES | NOVARTIS AG (CH) | 2008-10-09 | — | — | WO | disclosed |