⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28733425 | 0.98 | FDPS (0.43) | — | |
| SCHEMBL8670940 | 0.81 | ADRA2A (0.44) | — | |
| SCHEMBL7406981 | 0.77 | — | — | |
| SCHEMBL2849057 | 0.77 | — | — | |
| SCHEMBL708660 | 0.75 | ADRA2A (0.56) | — | |
| SCHEMBL7340791 | 0.73 | — | — | |
| SCHEMBL2787049 | 0.72 | ALDH1A1 (0.32) | — | |
| SCHEMBL8310366 | 0.72 | ADRA2A (0.48) | — | |
| SCHEMBL7342763 | 0.71 | FFAR2 (0.46) | — | |
| SCHEMBL2981194 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 389 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110520127-A | Piperidinyl-substituted and piperazinyl-substituted heteroaromatic carboxamides as modulators of GPR6 | TAKEDA PHARMACEUTICALS CO | 2019-11-29 | — | — | CN | claimed |
| CN-109939113-A | Bicyclic bromine structural domain inhibitor | 齐尼思表观遗传学有限公司 | 2019-06-28 | — | — | CN | claimed |
| CN-105407888-B | Novel bicyclic bromodomain inhibitors | 齐尼思表观遗传学有限公司 | 2019-05-21 | — | — | CN | claimed |
| CN-109476637-A | heterocyclic Prolinamide derivatives | 奥瑞恩眼科有限责任公司 | 2019-03-15 | — | — | CN | claimed |
| CN-105431418-B | Metalloenzyme Inhibitor Compounds | 北卡罗来纳维亚梅特制药公司 | 2019-02-05 | — | — | CN | claimed |
| CN-106029639-B | Treat 2- amino -3,5 of the BACE1 inhibitor of Alzheimer disease, 5- tri- fluoro- 3,4,5,6- tetrahydropyridines | H.隆德贝克有限公司 | 2019-01-08 | — | — | CN | claimed |
| CN-105283443-B | Hete rocyclic derivatives and application thereof | 株式会社C&C新药研究所 | 2018-08-17 | — | — | CN | claimed |
| CN-108368089-A | Novel Compounds | 特殊治疗有限公司 | 2018-08-03 | — | — | CN | claimed |
| CN-108314680-A | One kind containing aromatic compound, preparation method, pharmaceutical composition and application | 凯惠科技发展(上海)有限公司 | 2018-07-24 | — | — | CN | claimed |
| CN-105518005-B | Tricyclic pyridine-carboxamide derivatives as ROCK inhibitors | 百时美施贵宝公司 | 2018-07-20 | — | — | CN | claimed |
| EP-0626983-B1 | POLYMERIC BLENDS WITH ZWITTERIONIC GROUPS | BIOCOMPATIBLES LTD (GB) | 1999-04-14 | — | — | EP | claimed |
| EP-0714417-B1 | POLYMER SURFACE COATINGS | BIOCOMPATIBLES LTD (GB) | 1998-06-10 | — | — | EP | claimed |
| US-5712326-A | TO IMPROVE BIOCOMPATIBILITY; REDUCE FIBRINOGEN ABSORPTION AND/OR PLATELET ACTIVATION | BIOCOMPATIBLES LIMITED (GB) | 1998-01-27 | — | — | US | claimed |
| US-5645883-A | Zwitterionic materials | BIOCOMPATIBLES LIMITED (GB) | 1997-07-08 | — | — | US | claimed |
| EP-0714417-A1 | POLYMER SURFACE COATINGS | BIOCOMPATIBLES LIMITED (GB) | 1996-06-05 | — | — | EP | claimed |
| EP-0681486-A1 | NEW ZWITTERIONIC MATERIALS | BIOCOMPATIBLES LIMITED (GB) | 1995-11-15 | — | — | EP | claimed |
| WO-1995005408-A1 | POLYMER SURFACE COATINGS | BIOCOMPATIBLES LIMITED (GB) | 1995-02-23 | — | — | WO | claimed |
| EP-0626983-A1 | POLYMERIC BLENDS WITH ZWITTERIONIC GROUPS | BIOCOMPATIBLES LIMITED (GB) | 1994-12-07 | — | — | EP | claimed |
| WO-1994016749-A1 | NEW ZWITTERIONIC MATERIALS | BIOCOMPATIBLES LIMITED (GB) | 1994-08-04 | — | — | WO | claimed |
| WO-1994014897-A1 | POLYMERIC BLENDS WITH ZWITTERIONIC GROUPS | BIOCOMPATIBLES LIMITED (GB) | 1994-07-07 | — | — | WO | claimed |