Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 5/20 | 0.34 |
| ▸ | AXL | P30530 | 5/20 | 0.33 |
| ▸ | TYRO3 | Q06418 | 5/20 | 0.33 |
| ▸ | MERTK | Q12866 | 5/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5341621 | 1.00 | ABCC9 (0.34) | ABCC9AXLTYRO3MERTKHTR6 | |
| SCHEMBL3097671 | 0.92 | HTR6 (0.33) | ABCC9AXLTYRO3MERTKHTR6 | |
| SCHEMBL5338954 | 0.92 | HTR6 (0.33) | ABCC9AXLTYRO3MERTKHTR6 | |
| SCHEMBL8142517 | 0.92 | AXL (0.33) | ABCC9AXLTYRO3MERTK | |
| Water SCHEMBL5002583 | 0.91 | HTR6 (0.33) | ABCC9AXLTYRO3MERTKHTR6 | |
| SCHEMBL8147486 | 0.89 | ABCC9 (0.33) | ABCC9 | |
| SCHEMBL8149616 | 0.89 | POLB (0.38) | ABCC9AXLTYRO3MERTK | |
| SCHEMBL8142354 | 0.88 | HTR6 (0.34) | ABCC9AXLTYRO3MERTKHTR6 | |
| SCHEMBL14336961 | 0.84 | HTR6 (0.34) | ABCC9AXLTYRO3MERTKHTR6 | |
| SCHEMBL8155414 | 0.83 | ABCC9 (0.33) | ABCC9PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5912244-A | MUSCLE DISORDERS, BREATHING DISORDERS AND URINARY INCONTINENCE | PFIZER INC. (US) | 1999-06-15 | — | — | US | claimed |
| EP-0712398-B1 | BENZOPYRANS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PFIZER LTD (GB) | 1997-05-07 | — | — | EP | claimed |
| US-20090143393-A1 | METHOD OF STIMULATING HAIR GROWTH | PFIZER INC | 2009-06-04 | — | — | US | disclosed |
| US-20090143393-A1 | METHOD OF STIMULATING HAIR GROWTH | PFIZER INC | 2009-06-04 | — | — | US | disclosed |
| US-6071938-A | FOR TREATMENT OF SMOOTH MUSCLE DISORDERS | PFIZER INC. (US) | 2000-06-06 | — | — | US | disclosed |
| US-5912244-A | MUSCLE DISORDERS, BREATHING DISORDERS AND URINARY INCONTINENCE | PFIZER INC. (US) | 1999-06-15 | — | — | US | disclosed |
| EP-0712398-B1 | BENZOPYRANS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PFIZER LTD (GB) | 1997-05-07 | — | — | EP | disclosed |
| EP-0712398-A1 | BENZOPYRANS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PFIZER LTD (GB) | 1996-05-22 | — | — | EP | disclosed |
| WO-1995004730-A1 | BENZOPYRANS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PFIZER LIMITED (GB) | 1995-02-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090143393-A1 | METHOD OF STIMULATING HAIR GROWTH | HDGF, NGF, TPH2 | ABCC9 4843/4885AXL 4276/4885TYRO3 716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.