Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 10/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TOP2A | P11388 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | WEE1 | P30291 | 1/20 | 0.37 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.36 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8085334 | 0.88 | ALOX5 (0.66) | ALOX5MEN1KMT2ATOP2APTGS2 | |
| SCHEMBL8028888 | 0.81 | ALOX5 (0.80) | ALOX5MEN1KMT2ATOP2APTGS2 | |
| SCHEMBL8084885 | 0.80 | PTGS2 (0.44) | ALOX5MEN1KMT2APTGS2CHEK1 | |
| SCHEMBL8085182 | 0.75 | ALOX5 (0.49) | ALOX5MEN1KMT2ATOP2A | |
| SCHEMBL8086701 | 0.72 | ALOX5 (0.46) | ALOX5KMT2AGSK3BCHEK1WEE1 | |
| SCHEMBL2959109 | 0.72 | ALOX5 (0.48) | ALOX5MEN1KMT2APTGS2 | |
| SCHEMBL8080438 | 0.70 | ALOX5 (0.52) | ALOX5MEN1KMT2ATOP2A | |
| SCHEMBL8085136 | 0.69 | CHEK1 (0.35) | MEN1KMT2ACHEK1WEE1 | |
| SCHEMBL8085088 | 0.68 | ALOX5 (1.00) | ALOX5MEN1KMT2ATOP2A | |
| SCHEMBL8085105 | 0.68 | TDP2 (0.39) | ALOX5MEN1KMT2APTGS2MAP2K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000072696-A | PRODUCTION OF NAPHTHALENE DERIVATIVE, AND INTERMEDIATE THEREFOR | TAKEDA CHEM IND LTD | 2000-03-07 | — | — | JP | disclosed |