Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | BAX | Q07812 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9709765 | 0.73 | CA4 (0.53) | LTA4HTSHRCA4KCNA3CA5A | |
| Diphenylether SCHEMBL8157951 | 0.69 | LTA4H (0.86) | LTA4HTSHRCA4NR1H2BAX | |
| Hydrochloric Acid SCHEMBL6060212 | 0.69 | LTA4H (0.53) | LTA4HTSHRCA4KCNA3CA5A | |
| Diphenylether SCHEMBL8462019 | 0.69 | LTA4H (0.86) | LTA4HTSHRCA4NR1H2BAX | |
| Diphenylether SCHEMBL11437632 | 0.69 | LTA4H (0.86) | LTA4HTSHRCA4NR1H2BAX | |
| Iodide SCHEMBL8053431 | 0.69 | LMNA (0.40) | TSHRALDH1A1 | |
| Diphenylether SCHEMBL9061108 | 0.67 | LTA4H (1.00) | LTA4HTSHRCA4NR1H2BAX | |
| SCHEMBL14905 | 0.67 | LTA4H (0.60) | LTA4HTSHRCA4KCNA3CA5A | |
| Diphenylether SCHEMBL2461810 | 0.67 | LTA4H (1.00) | LTA4HTSHRCA4NR1H2BAX | |
| Diphenylether SCHEMBL4950525 | 0.67 | LTA4H (1.00) | LTA4HTSHRCA4NR1H2BAX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10100136-B2 | Organometallic compound in solid form, process for preparing the same and use thereof | INDIAN OIL CORPORATION LIMITED (IN) | 2018-10-16 | — | — | US | claimed |
| EP-3059261-B1 | PROCESS FOR PREPARING A CATALYST FOR OLEFIN POLYMERIZATION AND POLYMERIZATION | INDIAN OIL CORP LTD (IN) | 2018-10-03 | — | — | EP | claimed |
| US-9896523-B2 | Ziegler-Natta catalyst synthesis and process thereof | INDIAN OIL CORPORATION LIMITED (IN) | 2018-02-20 | — | — | US | claimed |
| US-9758602-B2 | Catalyst for olefin polymerization and polymerization thereof | INDIAN OIL CORPORATION LIMITED (IN) | 2017-09-12 | — | — | US | claimed |
| EP-3162819-A1 | IMPROVED ZIEGLER-NATTA CATALYST SYNTHESIS AND PROCESS THEREOF | Indian Oil Corporation Limited (IN) | 2017-05-03 | — | — | EP | claimed |
| US-20160376384-A1 | ZIEGLER-NATTA CATALYST SYNTHESIS AND PROCESS THEREOF | INDIAN OIL CORPORATION LIMITED (IN) | 2016-12-29 | — | — | US | claimed |
| EP-3162819-B1 | IMPROVED ZIEGLER-NATTA CATALYST SYNTHESIS AND PROCESS THEREOF | INDIAN OIL CORP LTD (IN) | 2018-09-05 | — | — | EP | disclosed |
| US-9896523-B2 | Ziegler-Natta catalyst synthesis and process thereof | INDIAN OIL CORPORATION LIMITED (IN) | 2018-02-20 | — | — | US | disclosed |
| EP-3162819-A1 | IMPROVED ZIEGLER-NATTA CATALYST SYNTHESIS AND PROCESS THEREOF | Indian Oil Corporation Limited (IN) | 2017-05-03 | — | — | EP | disclosed |
| US-20160376384-A1 | ZIEGLER-NATTA CATALYST SYNTHESIS AND PROCESS THEREOF | INDIAN OIL CORPORATION LIMITED (IN) | 2016-12-29 | — | — | US | disclosed |
| US-6077804-A | Olefin polymerization catalyst and process for preparing polyolefins | NIPPON OIL COMPANY, LIMITED (JP) | 2000-06-20 | — | — | US | disclosed |
| US-5780562-A | GROUP 4 METAL ALKOXIDE DERIVATIVES COMPLEXED WITH GROUP 1-3 METAL ALKOXIDE DERIVATIVES, ORGANOCYCLIC COMPOUNDS HAVING CONJUGATED BONDS, ALUMOXANES, AND A SLILICA OR ALUMINA | NIPPON OIL CO., LTD. (JP) | 1998-07-14 | — | — | US | disclosed |
| EP-0694563-A1 | Olefin polymerization catalyst and process for preparing polyolefins | NIPPON OIL COMPANY, LIMITED (JP) | 1996-01-31 | — | — | EP | disclosed |
| US-4824979-A | Method for the preparation of partial esters and ortho esters of titanium, zirconium or hafnium | HUELS TROISDORF AG (DE) | 1989-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10100136-B2 | Organometallic compound in solid form, process for preparing the same and use thereof | MLX, BRIX1, CYP4X1 | LTA4H 1162/4885TSHR 2774/4885CA4 1062/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.