Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 6/20 | 0.47 |
| ▸ | MMP13 | P45452 | 6/20 | 0.47 |
| ▸ | MMP9 | P14780 | 4/20 | 0.47 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 8/20 | 0.42 |
| ▸ | MMP7 | P09237 | 4/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 3/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.38 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7447815 | 0.90 | LMNA (0.43) | MMP1MMP13MMP9LMNAHPGD | |
| SCHEMBL4671560 | 0.90 | LMNA (0.43) | MMP1MMP13MMP9LMNAHPGD | |
| SCHEMBL4676634 | 0.85 | LMNA (0.43) | MMP1MMP13MMP9LMNAHPGD | |
| SCHEMBL4674820 | 0.83 | LMNA (0.43) | MMP1MMP13MMP9LMNAHPGD | |
| SCHEMBL4673925 | 0.83 | LMNA (0.43) | MMP1MMP13MMP9LMNAHPGD | |
| SCHEMBL4673963 | 0.82 | MMP1 (0.52) | MMP1MMP13MMP9ADAM17LMNA | |
| SCHEMBL4675079 | 0.81 | MMP3 (0.50) | MMP1MMP13MMP9LMNAHPGD | |
| SCHEMBL7325403 | 0.81 | MMP14 (0.42) | MMP1MMP13MMP9MMP3MMP7 | |
| SCHEMBL4671727 | 0.80 | MMP2 (0.41) | LMNAHPGDMAPTSMN1; SMN2MMP3 | |
| SCHEMBL4731774 | 0.80 | MMP2 (0.41) | LMNAHPGDMAPTSMN1; SMN2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6130220-A | ENZYME INHIBITORS | SYNTEX (USA) INC. (US) | 2000-10-10 | — | — | US | disclosed |