Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 5/20 | 0.52 |
| ▸ | CES1 | P23141 | 5/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 4/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL818007 | 0.90 | CES2 (0.56) | CES2CES1ATMESR1PTGS2 | |
| SCHEMBL6324909 | 0.87 | HSD17B3 (0.43) | CES2CES1ESR1PTGS2SMN1; SMN2 | |
| SCHEMBL815083 | 0.86 | PTGS2 (0.57) | CES2CES1ATMESR1PTGS2 | |
| SCHEMBL451258 | 0.85 | ATM (0.54) | CES2CES1ATMESR1PTGS2 | |
| SCHEMBL815888 | 0.85 | CES2 (0.56) | CES2CES1ESR1PTGS2LMNA | |
| SCHEMBL5390647 | 0.84 | CES2 (0.50) | CES2CES1ATMESR1PTGS2 | |
| SCHEMBL814748 | 0.83 | CES2 (0.58) | CES2CES1PTGS2L3MBTL1LMNA | |
| SCHEMBL817443 | 0.82 | PTGS2 (0.57) | CES2CES1ESR1PTGS2SMN1; SMN2 | |
| SCHEMBL6062883 | 0.80 | ALDH1A1 (0.50) | CES2CES1ATMSMN1; SMN2L3MBTL1 | |
| SCHEMBL8994830 | 0.80 | CES2 (0.47) | CES2CES1ESR1PTGS2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106065003-A | Sorbitol derivatives and its synthetic dbs kinds of polyolefin nucleating agent and its preparation method and application thereof | 苏州亚培克生物科技有限公司 | 2016-11-02 | — | — | CN | claimed |
| EP-2797996-A1 | REFLECTOR FOR LIGHT-EMITTING DEVICES | Ticona LLC (US) | 2014-11-05 | — | — | EP | claimed |
| WO-2013101277-A1 | REFLECTOR FOR LIGHT-EMITTING DEVICES | TICONA LLC (US) | 2013-07-04 | — | — | WO | claimed |
| US-7247687-B2 | Late transition metal catalysts for olefin polymerization and oligomerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-07-24 | — | — | US | claimed |
| EP-1521758-B1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | EXXONMOBIL CHEM PATENTS INC (US) | 2006-05-24 | — | — | EP | claimed |
| US-20060047094-A1 | Late transition metal catalysts for olefin polymerization and oligomerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2006-03-02 | — | — | US | claimed |
| EP-1521758-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | Exxonmobil Chemical Patents Inc. (US) | 2005-04-13 | — | — | EP | claimed |
| WO-2004007509-A1 | LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-01-22 | — | — | WO | claimed |
| EP-3066065-A1 | CATALYTIC HYDROGENATION FOR PRODUCING AMINES FROM CARBOXYLIC ACID AMIDES, CARBOXYLIC ACID DIAMIDES, DI-, TRI-, OR POLYPEPETIDES, OR PEPTIDE AMIDES | Evonik Degussa GmbH (DE) | 2016-09-14 | — | — | EP | disclosed |
| EP-1960411-B1 | HALOGEN SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION | EXXONMOBIL CHEM PATENTS INC (US) | 2016-08-31 | — | — | EP | disclosed |
| US-9163046-B2 | Process for producing substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2015-10-20 | — | — | US | disclosed |
| WO-2015067450-A1 | CATALYTIC HYDROGENATION FOR PRODUCING AMINES FROM CARBOXYLIC ACID AMIDES, CARBOXYLIC ACID DIAMIDES, DI-, TRI-, OR POLYPEPETIDES, OR PEPTIDE AMIDES | EVONIK INDUSTRIES AG (DE) | 2015-05-14 | — | — | WO | disclosed |
| EP-2797996-A1 | REFLECTOR FOR LIGHT-EMITTING DEVICES | Ticona LLC (US) | 2014-11-05 | — | — | EP | disclosed |
| US-8546595-B2 | Halogen substituted heteroatom-containing metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2013-10-01 | — | — | US | disclosed |
| US-4069377-A | Polymerization of ethylenically unsaturated monomers employing secondary-aliphatic α-substituted azoalkanes | PENNWALT CORPORATION | 1978-01-17 | — | — | US | disclosed |
| US-4048423-A | Process for polymerizing unsaturated monomers and unsaturated polyester resins employing unsymmetrical tertiary-aliphatic azoalkanes | PENNWALT CORPORATION (US) | 1977-09-13 | — | — | US | disclosed |
| US-4025502-A | POLYMERIZATION CATALYSTS, CURING AGENTS | PENNWALT CORPORATION (US) | 1977-05-24 | — | — | US | disclosed |
| US-4009157-A | POLYESTER FOAMING AGENTS, FREE RADICAL CATALYSTS | PENNWALT CORPORATION (US) | 1977-02-22 | — | — | US | disclosed |
| US-4007165-A | VINYL POLYMERIZATION INITIATORS POLYESTER CURING AGENTS | PENNWALT CORPORATION (US) | 1977-02-08 | — | — | US | disclosed |
| US-3992368-A | FROM A HYDRAZONE | PENNWALT CORPORATION (US) | 1976-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060047094-A1 | Late transition metal catalysts for olefin polymerization and oligomerization | MLX, LOX, LMTK3 | CES2 4281/4885CES1 4486/4885ATM 3933/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.