SCHEMBL8150872

SCHEMBL8150872

Cc1cc(Cc2cc(Cc3cc(C)cc(-c4ccc(O)cc4)c3O)c(O)c(C3CCCCC3)c2)c(O)c(-c2ccc(O)cc2)c1

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
NUDT1 P36639 1/20 0.34
BACE1 P56817 1/20 0.34
AMY1A P0DUB6 1/20 0.33
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33
ALOX5 P09917 1/20 0.32
PTGDR2 Q9Y5Y4 1/20 0.31
HSPA5 P11021 1/20 0.31
PTGS2 P35354 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
HIF1A Q16665 1/20 0.30
IDH1 O75874 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2385696 0.88 NUDT1 (0.39) NUDT1BACE1AMY1AESR1ESR2
SCHEMBL8150433 0.81 OPRM1 (0.38) NUDT1BACE1AMY1AESR1ESR2
SCHEMBL4061548 0.80 NUDT1 (0.44) NUDT1BACE1ESR1ESR2CYP2C9
SCHEMBL8141767 0.80 NUDT1 (0.40) NUDT1BACE1ESR1ESR2HSPA5
SCHEMBL2676397 0.80 AMY1A (0.54) NUDT1BACE1AMY1APTGDR2HSPA5
SCHEMBL29628813 0.80 AMY1A (0.54) NUDT1BACE1AMY1APTGDR2HSPA5
SCHEMBL29636453 0.80 AMY1A (0.54) NUDT1BACE1AMY1APTGDR2HSPA5
SCHEMBL2386130 0.79 SHBG (0.43) NUDT1BACE1ESR1ESR2CYP2C9
SCHEMBL29381510 0.78 AMY1A (0.43) NUDT1BACE1AMY1APTGDR2HSPA5
SCHEMBL34995 0.78 AMY1A (0.43) NUDT1BACE1AMY1APTGDR2HSPA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6127087-A COMPOSITION COMPRISING ALKALI-SOLUBLE RESIN, SPECIFIED QUINONEDIAZIDE COMPOUND TOKYO OHKA KOGYO CO., LTD. (JP) 2000-10-03 US disclosed