Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.54 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29636453 | 1.00 | AMY1A (0.54) | AMY1ANUDT1BACE1PTGDR2NPC1 | |
| SCHEMBL29628813 | 1.00 | AMY1A (0.54) | AMY1ANUDT1BACE1PTGDR2NPC1 | |
| SCHEMBL29695928 | 0.87 | BACE1 (0.46) | AMY1ANUDT1BACE1HSP90AA1CYP2C19 | |
| SCHEMBL9445214 | 0.85 | NUDT1 (0.43) | AMY1ANUDT1BACE1PTGDR2NPC1 | |
| SCHEMBL1276251 | 0.84 | AMY1A (0.42) | AMY1ANUDT1BACE1PTGDR2NPC1 | |
| SCHEMBL2545354 | 0.84 | AMY1A (0.50) | AMY1ANUDT1BACE1PTGDR2NPC1 | |
| SCHEMBL2385696 | 0.84 | NUDT1 (0.39) | AMY1ANUDT1BACE1PTGDR2NPC1 | |
| SCHEMBL27221198 | 0.83 | AMY1A (0.51) | AMY1ANUDT1BACE1PTGDR2NPC1 | |
| SCHEMBL29908289 | 0.82 | AMY1A (0.48) | AMY1ANUDT1BACE1PTGDR2NPC1 | |
| SCHEMBL3199214 | 0.82 | AMY1A (0.48) | AMY1ANUDT1BACE1PTGDR2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260062580-A1 | REVERSIBLY THERMOCHROMIC COMPOSITION, REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING REVERSIBLY THERMOCHROMIC COMPOSITION, AND WRITING INSTRUMENT USING REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT | THE PILOT INK CO., LTD. (JP) | 2026-03-05 | — | — | US | disclosed |
| EP-3954745-B1 | REVERSIBLY THERMOCHROMIC AQUEOUS INK COMPOSITION FOR WRITING UTENSILS, AND REFILL AND WATER-BASED BALLPOINT PEN EACH INTERNALLY CONTAINING SAME | KK PILOT CORPORATION ALSO TRADING AS PILOT CORPORATION (JP) | 2026-01-07 | — | — | EP | disclosed |
| US-12497558-B2 | Colour change composition and compounds | THERMOGRAPHIC MEASUREMENTS LTD (GB) | 2025-12-16 | — | — | US | disclosed |
| US-12460099-B2 | Reversibly thermochromic composition, reversibly thermochromic microcapsule pigment encapsulating reversibly thermochromic composition, and writing instrument using reversibly thermochromic microcapsule pigment | THE PILOT INK CO., LTD. (JP) | 2025-11-04 | — | — | US | disclosed |
| US-12421411-B2 | Aqueous ink composition for reversibly thermochromic writing instrument, and refill and aqueous ballpoint pen incorporating aqueous ink composition for reversibly thermochromic writing instrument | KABUSHIKI KAISHA PILOT CORPORATION (JP) | 2025-09-23 | — | — | US | disclosed |
| US-12421349-B2 | Polyphenylene ether composition | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2025-09-23 | — | — | US | disclosed |
| US-12297357-B2 | Temperature-sensitive indicator | THERMOGRAPHIC MEASUREMENTS LTD (GB) | 2025-05-13 | — | — | US | disclosed |
| EP-3344468-B1 | COMPOUND FOR USE IN COLOUR CHANGE COMPOSITIONS | THERMOGRAPHIC MEASUREMENTS LTD (GB) | 2025-03-05 | — | — | EP | disclosed |
| US-12202981-B2 | Compound for use in colour change compositions | SOCIETE BIC (FR) | 2025-01-21 | — | — | US | disclosed |
| EP-4306571-B1 | POLYPHENYLENE ETHER, METHOD FOR PRODUCING SAME, THERMALLY CURABLE COMPOSITION, PREPREG, AND MULTILAYER BODY | ASAHI CHEMICAL IND (JP) | 2024-12-25 | — | — | EP | disclosed |
| US-20090050013-A1 | writing implement; homogeneous solubilized mixture of an electron donative coloring organic compound, an electron accepting compound and an ester of a 2-[p-(benxyloxy)phenyl]ethyl alcohol to control color reactions of the first two components | THE PILOT INK CO., LTD. (JP) | 2009-02-26 | — | — | US | disclosed |
| US-7494537-B2 | Thermochromic coloring color-memory composition and thermochromic coloring color-memory microcapsule pigment containing the same | THE PILOT INK CO., LTD. (JP) | 2009-02-24 | — | — | US | disclosed |
| EP-1657073-B1 | Reversible thermochromic composition and microcapsules containing the same | PILOT INK CO LTD (JP) | 2008-02-27 | — | — | EP | disclosed |
| US-20070213499-A1 | Polyfunctional phenylene ether oligomer, derivative thereof, resin composition containing the same, and use thereof | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2007-09-13 | — | — | US | disclosed |
| EP-1832617-A2 | Polyfunctional phenylene ether oligomer, derivative thereof, resin composition containing the same, and use thereof | Mitsubishi Gas Chemical Company, Inc. (JP) | 2007-09-12 | — | — | EP | disclosed |
| EP-1477320-B1 | Thermochromic color-memory composition, ink, and microencapsulated pigment containing the same | PILOT INK CO LTD (JP) | 2007-09-05 | — | — | EP | disclosed |
| US-20060112851-A1 | Thermochromic coloring color-memory composition and thermochromic coloring color-memory microcapsule pigment containing the same | THE PILOT INK CO., LTD. | 2006-06-01 | — | — | US | disclosed |
| EP-1657073-A2 | Reversible thermochromic composition and microcapsules containing the same | THE PILOT INK CO., LTD. (JP) | 2006-05-17 | — | — | EP | disclosed |
| US-20040229754-A1 | homogeneous solubilized mixture of an electron donative coloring organic compound, an electron accepting compound and a fatty acid ester of a 2-[p-(benxyloxy)phenyl]ethyl alcohol to control color reactions of the first two components | THE PILOT INK CO., LTD. | 2004-11-18 | — | — | US | disclosed |
| EP-1477320-A2 | Thermochromic color-memory composition and microencapsulated pigment containing the same | THE PILOT INK CO., LTD. (JP) | 2004-11-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12297357-B2 | Temperature-sensitive indicator | NCS1, TREH, NEFM | AMY1A 784/4885NUDT1 905/4885BACE1 774/4885 |
| US-20260062580-A1 | REVERSIBLY THERMOCHROMIC COMPOSITION, REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING REVERSIBLY THERMOCHROMIC COMPOSITION, AND WRITING INSTRUMENT USING REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT | TYR, SCO2, HBB | AMY1A 80/4885NUDT1 1610/4885BACE1 4659/4885 |
| US-12202981-B2 | Compound for use in colour change compositions | TYR, C1R, CBR3 | AMY1A 531/4885NUDT1 1470/4885BACE1 3206/4885 |
| US-12497558-B2 | Colour change composition and compounds | C5, C9, C3AR1 | AMY1A 674/4885NUDT1 3205/4885BACE1 382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.