Known targets — ChEMBL curated mechanism
ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of 1,3-Propanediol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | SNCA | P37840 | 1/20 | 0.46 |
| ▸ | G6PD | P11413 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,3-Propanediol SCHEMBL3302630 | 1.00 | ALDH1A1 (0.50) | ALDH1A1CYP2C9CYP3A4CYP2C19SMN1; SMN2 | |
| 1,4-Butanediol SCHEMBL8461121 | 0.96 | ALDH1A1 (0.50) | ALDH1A1CYP2C9CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL10618328 | 0.94 | ALDH1A1 (0.48) | ALDH1A1CYP2C9CYP3A4CYP2C19SMN1; SMN2 | |
| 1,5-Pentanediol SCHEMBL28493250 | 0.94 | ALDH1A1 (0.48) | ALDH1A1CYP2C9CYP3A4CYP2C19SMN1; SMN2 | |
| 1,6-Hexanediol SCHEMBL28193578 | 0.94 | ALDH1A1 (0.48) | ALDH1A1CYP2C9CYP3A4CYP2C19SMN1; SMN2 | |
| 1,5-Pentanediol SCHEMBL3465348 | 0.94 | ALDH1A1 (0.48) | ALDH1A1CYP2C9CYP3A4CYP2C19SMN1; SMN2 | |
| 1,6-Hexanediol SCHEMBL28498786 | 0.94 | ALDH1A1 (0.48) | ALDH1A1CYP2C9CYP3A4CYP2C19SMN1; SMN2 | |
| Ethylene Glycol SCHEMBL1617625 | 0.91 | GAA (0.52) | ALDH1A1CYP2C9CYP3A4CYP2C19SMN1; SMN2 | |
| Ethylene Glycol SCHEMBL241885 | 0.91 | GAA (0.52) | ALDH1A1CYP2C9CYP3A4CYP2C19SMN1; SMN2 | |
| Ethylene Glycol SCHEMBL1936216 | 0.91 | GAA (0.52) | ALDH1A1CYP2C9CYP3A4CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11286490-A | — | — | None | — | — | JP | disclosed |
| WO-2025070154-A1 | POLYAMIDE RESIN, PHOTOSENSITIVE RESIN COMPOSITION, CURED PRODUCT AND METHOD FOR PRODUCING SAME, AND ELECTRONIC COMPONENT | 東レ株式会社 | 2025-04-03 | — | — | WO | disclosed |
| WO-2025063188-A1 | PHOTOSENSITIVE RESIN COMPOSITION, CURED PRODUCT, ORGANIC EL DISPLAY DEVICE, AND METHOD FOR PRODUCING CURED PRODUCT | 東レ株式会社 | 2025-03-27 | — | — | WO | disclosed |
| WO-2024171805-A1 | POLYIMIDE RESIN, PHOTOSENSITIVE RESIN COMPOSITION, CURED PRODUCT, ORGANIC EL DISPLAY DEVICE, AND ELECTRONIC COMPONENT | 東レ株式会社 | 2024-08-22 | — | — | WO | disclosed |
| CN-115298227-B | Group III and lanthanide bis-phenyl-phenoxy metal-ligand complexes | 陶氏环球技术有限责任公司 | 2024-06-04 | — | — | CN | disclosed |
| CN-118020025-A | Photosensitive resin composition, cured product, organic EL display device, semiconductor device, and method for producing cured product | 东丽株式会社 | 2024-05-10 | — | — | CN | disclosed |
| CN-117069749-A | Group III and lanthanide bis-phenyl-phenoxy metal-ligand complexes | 陶氏环球技术有限责任公司 | 2023-11-17 | — | — | CN | disclosed |
| WO-2023182327-A1 | POSITIVE PHOTOSENSITIVE RESIN COMPOSITION, CURED PRODUCT, ORGANIC EL DISPLAY DEVICE, AND METHOD FOR PRODUCING CURED PRODUCT | 東レ株式会社 | 2023-09-28 | — | — | WO | disclosed |
| WO-2023095785-A1 | PHOTOSENSITIVE RESIN COMPOSITION, CURED ARTICLE, ORGANIC EL DISPLAY DEVICE, SEMICONDUCTOR DEVICE, AND METHOD FOR PRODUCING CURED ARTICLE | 東レ株式会社 | 2023-06-01 | — | — | WO | disclosed |
| CN-115298227-A | Group III and lanthanide bis-phenyl-phenoxy metal-ligand complexes | 陶氏环球技术有限责任公司 | 2022-11-04 | — | — | CN | disclosed |
| US-20110282018-A1 | PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR | DOW GLOBAL TECHNOLOGIES LLC | 2011-11-17 | — | — | US | disclosed |
| EP-2094633-A1 | HYDROFLUOROETH R COMPOUNDS AND PROCESSES FOR THEIR PREPARATION AND USE | 3M Innovative Properties Company (US) | 2009-09-02 | — | — | EP | disclosed |
| EP-2027100-A2 | CYCLIC HYDROFLUOROETHER COMPOUNDS AND PROCESSES FOR THEIR PREPARATION AND USE | 3M Innovative Properties Company (US) | 2009-02-25 | — | — | EP | disclosed |
| WO-2008083054-A2 | LIGANDS FOR CARDIAC BETA1 ADRENOCEPTOR FOR IMAGING CONGESTIVE HEART FAILURE | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2008-07-10 | — | — | WO | disclosed |
| WO-2008070606-A1 | HYDROFLUOROETHΞR COMPOUNDS AND PROCESSES FOR THEIR PREPARATION AND USE | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2008-06-12 | — | — | WO | disclosed |
| US-20080139683-A1 | HYDROFLUOROETHER COMPOUNDS AND PROCESSES FOR THEIR PREPARATION AND USE | 3M INNOVATIVE PROPERTIES COMPANY | 2008-06-12 | — | — | US | disclosed |
| WO-2007136948-A2 | CYCLIC HYDROFLUOROETHER COMPOUNDS AND PROCESSES FOR THEIR PREPARATION AND USE | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2007-11-29 | — | — | WO | disclosed |
| US-20070267464-A1 | CYCLIC HYDROFLUOROETHER COMPOUNDS AND PROCESSES FOR THEIR PREPARATION AND USE | 3M INNOVATIVE PROPERTIES COMPANY | 2007-11-22 | — | — | US | disclosed |
| US-6130330-A | Process for preparing macropolycyclic polyamines | CLARIANT GMBH (DE) | 2000-10-10 | — | — | US | disclosed |
| JP-H11286490-A | PRODUCTION OF MACROPOLYCYCLIC POLYAMIDE | CLARIANT GMBH | 1999-10-19 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070267464-A1 | CYCLIC HYDROFLUOROETHER COMPOUNDS AND PROCESSES FOR THEIR PREPARATION AND USE | AFF4, CYP4F3, CYP2F1 | ALDH1A1 2903/4885CYP2C9 576/4885CYP3A4 267/4885 |
| US-20080139683-A1 | HYDROFLUOROETHER COMPOUNDS AND PROCESSES FOR THEIR PREPARATION AND USE | OGFOD1, AQP3, FOS | ALDH1A1 2812/4885CYP2C9 1630/4885CYP3A4 1050/4885 |
| US-20110282018-A1 | PROCESS FOR SELECTIVELY POLYMERIZING ETHYLENE AND CATALYST THEREFOR | WEE2, NOTUM, WEE1 | ALDH1A1 2392/4885CYP2C9 4020/4885CYP3A4 553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.