Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCSK9 | Q8NBP7 | 2/20 | 0.37 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.35 |
| ▸ | ORAI2 | Q96SN7 | 2/20 | 0.35 |
| ▸ | ORAI3 | Q9BRQ5 | 2/20 | 0.35 |
| ▸ | TRPV6 | Q9H1D0 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenyl Methyl Borinic Acid SCHEMBL8160699 | 0.83 | — | — | |
| SCHEMBL7177934 | 0.82 | TRPV6 (0.52) | PCSK9ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL12266366 | 0.76 | ORAI1 (0.52) | PCSK9ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL12266163 | 0.75 | LPL (0.47) | TDP1 | |
| SCHEMBL7647715 | 0.73 | PCSK9 (0.61) | PCSK9ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL12266207 | 0.72 | SIGMAR1 (0.43) | TDP1 | |
| SCHEMBL5571942 | 0.71 | CYP1A2 (0.48) | ORAI1ORAI2ORAI3TDP1 | |
| SCHEMBL13383567 | 0.71 | CYP1A2 (0.42) | PCSK9ORAI1ORAI2ORAI3TRPV6 | |
| Phenylboronic Acid SCHEMBL3985819 | 0.70 | ENPP2 (0.56) | PCSK9ORAI1ORAI2ORAI3TRPV6 | |
| SCHEMBL14500178 | 0.68 | ALDH1A1 (0.41) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000018773-A1 | CHEMICAL COMPOUND | TARGOR GMBH (DE) | 2000-04-06 | — | — | WO | disclosed |