Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.32 |
| ▸ | CASP1 | P29466 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | CASP7 | P55210 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4722189 | 0.85 | ALDH1A1 (0.37) | ALDH1A1HSD17B10HIF1ACYP1B1KDM4E | |
| SCHEMBL145793 | 0.82 | ALDH1A1 (0.44) | ALDH1A1HSD17B10HIF1ACYP1B1HPGD | |
| SCHEMBL813887 | 0.74 | ALDH1A1 (0.39) | ALDH1A1HSD17B10HIF1ACYP1B1KDM4E | |
| SCHEMBL815116 | 0.74 | HSD17B10 (0.39) | ALDH1A1HSD17B10HIF1ACYP1B1HPGD | |
| SCHEMBL4277948 | 0.73 | GSTP1 (0.48) | ALDH1A1HSD17B10HIF1AKDM4EHPGD | |
| SCHEMBL816687 | 0.72 | HSD17B10 (0.41) | ALDH1A1HSD17B10HIF1ACYP1B1HPGD | |
| SCHEMBL216214 | 0.71 | ALDH1A1 (0.41) | ALDH1A1HSD17B10HIF1AKDM4EGAA | |
| SCHEMBL4848746 | 0.70 | ALDH1A1 (0.72) | ALDH1A1HSD17B10HIF1ACYP1B1KDM4E | |
| SCHEMBL29532882 | 0.70 | ALDH1A1 (0.72) | ALDH1A1HSD17B10HIF1ACYP1B1KDM4E | |
| SCHEMBL4853659 | 0.70 | ALDH1A1 (0.72) | ALDH1A1HSD17B10HIF1ACYP1B1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3539993-A1 | CYCLOPROPYL SUBSTITUTED METALLOCENE CATALYSTS | ExxonMobil Chemical Patents Inc. (US) | 2019-09-18 | — | — | EP | disclosed |
| EP-3022233-B1 | CYCLOPROPYL SUBSTITUTED METALLOCENE CATALYSTS | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2019-05-01 | — | — | EP | disclosed |
| US-20180066083-A1 | Cyclopropyl Substituted Metallocene Catalysts | EXXONMOBIL CHEMICAL PATENTS INC. | 2018-03-08 | — | — | US | disclosed |
| US-9834628-B2 | Cyclopropyl substituted metallocene catalysts | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2017-12-05 | — | — | US | disclosed |
| EP-1960411-B1 | HALOGEN SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION | EXXONMOBIL CHEM PATENTS INC (US) | 2016-08-31 | — | — | EP | disclosed |
| EP-3022233-A1 | CYCLOPROPYL SUBSTITUTED METALLOCENE CATALYSTS | ExxonMobil Chemical Patents Inc. (US) | 2016-05-25 | — | — | EP | disclosed |
| US-9163046-B2 | Process for producing substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2015-10-20 | — | — | US | disclosed |
| WO-2015009473-A1 | CYCLOPROPYL SUBSTITUTED METALLOCENE CATALYSTS | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2015-01-22 | — | — | WO | disclosed |
| US-20150025207-A1 | Cyclopropyl Substituted Metallocene Catalysts | EXXONMOBIL CHEMICAL PATENTS INC. | 2015-01-22 | — | — | US | disclosed |
| US-8546595-B2 | Halogen substituted heteroatom-containing metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2013-10-01 | — | — | US | disclosed |
| US-7538168-B2 | Halogen substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2009-05-26 | — | — | US | disclosed |
| US-7446216-B2 | Halogen substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2008-11-04 | — | — | US | disclosed |
| US-20070135595-A1 | Halogen substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS, INC. | 2007-06-14 | — | — | US | disclosed |
| US-20070135623-A1 | Halogen substituted heteroatom-containing metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-06-14 | — | — | US | disclosed |
| US-20070135594-A1 | Halogen substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-06-14 | — | — | US | disclosed |
| US-20070135596-A1 | Preparation of substituted bridged indenyl and related ligands | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-06-14 | — | — | US | disclosed |
| US-20070135593-A1 | Halogen substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2007-06-14 | — | — | US | disclosed |
| US-20060183874-A1 | Halogen substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2006-08-17 | — | — | US | disclosed |
| US-20060160967-A1 | Halogen substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2006-07-20 | — | — | US | disclosed |
| US-20060160968-A1 | Process for producing substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135623-A1 | Halogen substituted heteroatom-containing metallocene compounds for olefin polymerization | OPRM1, POLM, AP1M1 | ALDH1A1 3259/4885HSD17B10 2229/4885HIF1A 3911/4885 |
| US-20060183874-A1 | Halogen substituted metallocene compounds for olefin polymerization | B2M, CDYL, MLX | ALDH1A1 2587/4885HSD17B10 3297/4885HIF1A 1655/4885 |
| US-20070135596-A1 | Preparation of substituted bridged indenyl and related ligands | SP1, TTL, TTLL12 | ALDH1A1 2182/4885HSD17B10 3785/4885HIF1A 1209/4885 |
| US-20070135594-A1 | Halogen substituted metallocene compounds for olefin polymerization | MLX, AP1M1, AP2M1 | ALDH1A1 1617/4885HSD17B10 4194/4885HIF1A 3290/4885 |
| US-20070135595-A1 | Halogen substituted metallocene compounds for olefin polymerization | AP2M1, AP1M1, CPNE4 | ALDH1A1 1770/4885HSD17B10 4073/4885HIF1A 777/4885 |
| US-20180066083-A1 | Cyclopropyl Substituted Metallocene Catalysts | CPNE4, TIMM13, NECTIN4 | ALDH1A1 767/4885HSD17B10 1530/4885HIF1A 2446/4885 |
| US-20070135593-A1 | Halogen substituted metallocene compounds for olefin polymerization | ZKSCAN2, ZRANB2, ZC3H18 | ALDH1A1 1684/4885HSD17B10 3004/4885HIF1A 4380/4885 |
| US-20060160967-A1 | Halogen substituted metallocene compounds for olefin polymerization | OR10J3, ZRANB2, SLC39A3 | ALDH1A1 2730/4885HSD17B10 3592/4885HIF1A 4496/4885 |
| US-20060160968-A1 | Process for producing substituted metallocene compounds for olefin polymerization | OSBP, OSBPL3, OSBP2 | ALDH1A1 2387/4885HSD17B10 1142/4885HIF1A 2989/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.