Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5311399 | 0.84 | TSHR (0.33) | TSHRESR1ESR2KCNN4KMT2A | |
| SCHEMBL5314519 | 0.82 | ESR1 (0.35) | TSHRESR1ESR2MAPT | |
| SCHEMBL5313286 | 0.78 | KCNN4 (0.31) | KCNN4 | |
| SCHEMBL132933 | 0.72 | CES2 (0.43) | TSHRESR1ESR2CES2CES1 | |
| SCHEMBL679391 | 0.72 | PAX8 (0.36) | ESR1ESR2CES2CES1MAPT | |
| SCHEMBL11135678 | 0.68 | PAX8 (0.33) | ESR1ESR2KMT2ACES2CES1 | |
| SCHEMBL28890772 | 0.68 | ELANE (0.46) | TSHRKMT2ACES2CES1MTNR1A | |
| SCHEMBL1053507 | 0.68 | CES2 (0.39) | TSHRESR1KCNN4KMT2ACES2 | |
| SCHEMBL5702337 | 0.68 | CES2 (0.39) | TSHRESR1KCNN4KMT2ACES2 | |
| SCHEMBL37986 | 0.68 | CA4 (0.41) | TSHRESR1ESR2KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0622406-B1 | Silicone rubber compositions, their preparation and use | SHINETSU CHEMICAL CO (JP) | 1999-11-24 | — | — | EP | claimed |
| US-5504176-A | CURABLE MIXTURE OF POLYSILOXANE, AN ORGANIC SILICON CROSSLINKING AGENT AND A TIN COMPOUND AS CATALYST PROTECTED FROM THE AIR BY MICROENCAPSULATION BY A THERMOSETTING RESIN; STORAGE STABILITY; FAST AND DEEP CURE | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-04-02 | — | — | US | claimed |
| EP-0669376-B1 | Process for preparing a liquid silicone composition | SHINETSU CHEMICAL CO (JP) | 2000-01-19 | — | — | EP | disclosed |
| EP-0622406-B1 | Silicone rubber compositions, their preparation and use | SHINETSU CHEMICAL CO (JP) | 1999-11-24 | — | — | EP | disclosed |
| EP-0579494-B1 | Silicone rubber composition with improved fluidity | SHINETSU CHEMICAL CO (JP) | 1998-03-18 | — | — | EP | disclosed |
| US-5504176-A | CURABLE MIXTURE OF POLYSILOXANE, AN ORGANIC SILICON CROSSLINKING AGENT AND A TIN COMPOUND AS CATALYST PROTECTED FROM THE AIR BY MICROENCAPSULATION BY A THERMOSETTING RESIN; STORAGE STABILITY; FAST AND DEEP CURE | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-04-02 | — | — | US | disclosed |
| US-5504147-A | HEAT TREATING MIXTURE OF POLYSILOXANE HAVING REACTIVE MONOMERS, POLYSILOXANE ENDCAPPED WITH TRIMETHYLSILYL GROUP, SILICA FILLER AND HEXAMETHYLDISILAZANE YIELDS WORKABLE, STORAGE STABLE, LOW VISCOSITY, CURABLE RELEASING MATERIAL | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-04-02 | — | — | US | disclosed |
| EP-0669376-A2 | Process for preparing a liquid silicone composition | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-08-30 | — | — | EP | disclosed |
| EP-0622406-A1 | Silicone rubber compositions, their preparation and use | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1994-11-02 | — | — | EP | disclosed |
| US-5352724-A | Consists of alkenyl group containing organopolysiloxane, an organohydrogenpolysiloxane, platinum group catalyst, inorganic filler, organic titanic acid esters and silicic acid esters of titanium and water; | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1994-10-04 | — | — | US | disclosed |
| EP-0579494-A1 | Silicone rubber composition with improved fluidity | Shin-Etsu Chemical Co., Ltd. (JP) | 1994-01-19 | — | — | EP | disclosed |
| US-5236997-A | Curable fluorosilicone rubber composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1993-08-17 | — | — | US | disclosed |