Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5311399 | 0.78 | TSHR (0.33) | KCNN4 | |
| SCHEMBL8167351 | 0.78 | TSHR (0.33) | KCNN4 | |
| SCHEMBL31571908 | 0.77 | PAX8 (0.33) | — | |
| SCHEMBL5314519 | 0.77 | ESR1 (0.35) | — | |
| SCHEMBL476117 | 0.77 | CES2 (0.38) | KCNN4 | |
| SCHEMBL7599259 | 0.74 | ALDH1A1 (0.36) | KCNN4ABL1 | |
| SCHEMBL6072557 | 0.74 | ABL1 (0.35) | KCNN4ABL1 | |
| SCHEMBL704188 | 0.73 | MAPK1 (0.36) | KCNN4ABL1 | |
| SCHEMBL2184635 | 0.72 | ELANE (0.41) | — | |
| SCHEMBL560290 | 0.72 | HCAR2 (0.41) | KCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1471069-B1 | Preparation of silyl ketene acetals and disilyl ketene acetals | SHINETSU CHEMICAL CO (JP) | 2007-04-18 | — | — | EP | disclosed |
| US-7112710-B2 | Preparation of silyl ketene acetal and disilyl ketene acetal | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2006-09-26 | — | — | US | disclosed |
| US-20050256329-A1 | Preparation of silyl ketene acetal and disilyl ketene acetal | KIYOMORI AYUMU | 2005-11-17 | — | — | US | disclosed |
| US-6960679-B2 | Preparation of silyl ketene acetal and disilyl ketene acetal | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2005-11-01 | — | — | US | disclosed |
| US-20040215033-A1 | Preparation of silyl ketene acetal and disilyl ketene acetal | SHIN-ETSU CHEMICAL CO. LTD. (JP) | 2004-10-28 | — | — | US | disclosed |
| EP-1471069-A1 | Preparation of silyl ketene acetals and disilyl ketene acetals | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2004-10-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256329-A1 | Preparation of silyl ketene acetal and disilyl ketene acetal | TREH, DEGS1, PHYKPL | KCNN4 1459/4885ABL1 2406/4885 |
| US-20040215033-A1 | Preparation of silyl ketene acetal and disilyl ketene acetal | TREH, PHYKPL, KAT8 | KCNN4 1739/4885ABL1 2098/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.