Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.30 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5311399 | 0.82 | TSHR (0.33) | ESR1ESR2MAPTTSHR | |
| SCHEMBL8167351 | 0.82 | TSHR (0.33) | ESR1ESR2MAPTTSHR | |
| SCHEMBL9806235 | 0.82 | — | — | |
| SCHEMBL5313286 | 0.77 | KCNN4 (0.31) | — | |
| SCHEMBL22279924 | 0.74 | KMT2A (0.42) | ESR1ESR2MAPTTSHR | |
| SCHEMBL475969 | 0.74 | MAPT (0.43) | ESR1ESR2MAPTTSHR | |
| SCHEMBL48955 | 0.69 | ESR1 (0.41) | ESR1ESR2MAPTTSHRNR1H2 | |
| SCHEMBL1719096 | 0.69 | ELANE (0.45) | ESR1ESR2MAPTTSHR | |
| SCHEMBL475968 | 0.68 | MAPT (0.38) | ESR1ESR2MAPTTSHRNR1H2 | |
| SCHEMBL10535386 | 0.68 | MAPT (0.38) | ESR1ESR2MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023042894-A1 | FURANACRYLIC ACID ESTER POLYMER, PRODUCTION METHOD THEREFOR, AND POLYMERIZABLE MONOMER FOR USE IN PRODUCING SAID POLYMER AND PRODUCTION METHOD THEREFOR | 国立研究開発法人産業技術総合研究所 | 2023-03-23 | — | — | WO | disclosed |
| EP-1471069-B1 | Preparation of silyl ketene acetals and disilyl ketene acetals | SHINETSU CHEMICAL CO (JP) | 2007-04-18 | — | — | EP | disclosed |
| US-7112710-B2 | Preparation of silyl ketene acetal and disilyl ketene acetal | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2006-09-26 | — | — | US | disclosed |
| US-20050256329-A1 | Preparation of silyl ketene acetal and disilyl ketene acetal | KIYOMORI AYUMU | 2005-11-17 | — | — | US | disclosed |
| US-6960679-B2 | Preparation of silyl ketene acetal and disilyl ketene acetal | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2005-11-01 | — | — | US | disclosed |
| US-20040215033-A1 | Preparation of silyl ketene acetal and disilyl ketene acetal | SHIN-ETSU CHEMICAL CO. LTD. (JP) | 2004-10-28 | — | — | US | disclosed |
| EP-1471069-A1 | Preparation of silyl ketene acetals and disilyl ketene acetals | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2004-10-27 | — | — | EP | disclosed |
| EP-0424000-B1 | Novel silicone polymers, copolymers and block copolymers and a method for their preparation | DOW CORNING (US) | 1996-02-07 | — | — | EP | disclosed |
| US-5371147-A | Silicone-containing acrylic star polymers, block copolymers and macromonomers | PERMEABLE TECHNOLOGIES, INC. (US) | 1994-12-06 | — | — | US | disclosed |
| US-5331067-A | Acrylic polymers containing trimethylsiloxy groups | PERMEABLE TECHNOLOGIES, INC. (US) | 1994-07-19 | — | — | US | disclosed |
| EP-0278668-A2 | Polymerisation process | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-08-17 | — | — | EP | disclosed |
| US-4711942-A | FROM ACRYLIC OR MALEIMIDE MONOMER AND ORGANOSILICON,-TIN, OR -GERMANIUM INITIATOR | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-12-08 | — | — | US | disclosed |
| US-4681918-A | ACRYLIC-TYPE OR MALEIMIDE MONOMERS; ORGANOSILICON, TIN OR GERMANIUM INITIATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-07-21 | — | — | US | disclosed |
| EP-0068887-B1 | \"LIVING\" POLYMERS AND PROCESS FOR THEIR PREPARATION | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-09-24 | — | — | EP | disclosed |
| US-4581428-A | Process for preparing \"living\" polymers using tetracoordinate organosilicon, organotin or organogermanium polymerization initiator with bifluoride ion source co-catalyst | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-04-08 | — | — | US | disclosed |
| US-4524196-A | Process for preparing \"living\" polymers | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-06-18 | — | — | US | disclosed |
| US-4508880-A | ACRYLIC OR MALEIMIDE MONOMERS WITH ORGANOSILICON, (-TIN, OR-GERMANIUM) INITIATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-04-02 | — | — | US | disclosed |
| US-4417034-A | POLYMERIZING ACRYLIC OR MALEIMIDE MONOMERS WITH ORGANO-SILICON, -TIN, OR-GERMANIUM INITIATORS | E. I. DU PONT DE NEMOURS & CO. (US) | 1983-11-22 | — | — | US | disclosed |
| US-4414372-A | ADDITION POLYMERS WITH FUNCTIONAL END GROUPS | E. I. DU PONT DE NEMOURS & CO. (US) | 1983-11-08 | — | — | US | disclosed |
| EP-0068887-A1 | \"Living\" polymers and process for their preparation | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-01-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256329-A1 | Preparation of silyl ketene acetal and disilyl ketene acetal | TREH, DEGS1, PHYKPL | ESR1 2400/4885ESR2 1488/4885MAPT 4013/4885 |
| US-20040215033-A1 | Preparation of silyl ketene acetal and disilyl ketene acetal | TREH, PHYKPL, KAT8 | ESR1 2413/4885ESR2 2548/4885MAPT 4195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.