Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8167351 | 0.84 | TSHR (0.33) | TSHRESR1ESR2KCNN4KMT2A | |
| SCHEMBL5314519 | 0.82 | ESR1 (0.35) | TSHRESR1ESR2MAPT | |
| SCHEMBL5313286 | 0.78 | KCNN4 (0.31) | KCNN4 | |
| SCHEMBL476126 | 0.72 | CES2 (0.43) | TSHRESR1ESR2CES2CES1 | |
| SCHEMBL3244338 | 0.72 | PAX8 (0.36) | ESR1ESR2CES2CES1MAPT | |
| SCHEMBL704476 | 0.71 | CES2 (0.41) | TSHRESR1ESR2CES2CES1 | |
| SCHEMBL2144442 | 0.68 | HCAR2 (0.46) | TSHRKMT2AMAPT | |
| SCHEMBL2144436 | 0.68 | HCAR2 (0.46) | TSHRKMT2AMAPT | |
| SCHEMBL15843632 | 0.68 | KCNN4 (0.39) | TSHRKCNN4KMT2ACES2CES1 | |
| SCHEMBL2144573 | 0.68 | HCAR2 (0.46) | TSHRKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023042894-A1 | FURANACRYLIC ACID ESTER POLYMER, PRODUCTION METHOD THEREFOR, AND POLYMERIZABLE MONOMER FOR USE IN PRODUCING SAID POLYMER AND PRODUCTION METHOD THEREFOR | 国立研究開発法人産業技術総合研究所 | 2023-03-23 | — | — | WO | disclosed |
| EP-1471069-B1 | Preparation of silyl ketene acetals and disilyl ketene acetals | SHINETSU CHEMICAL CO (JP) | 2007-04-18 | — | — | EP | disclosed |
| US-7112710-B2 | Preparation of silyl ketene acetal and disilyl ketene acetal | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2006-09-26 | — | — | US | disclosed |
| US-20050256329-A1 | Preparation of silyl ketene acetal and disilyl ketene acetal | KIYOMORI AYUMU | 2005-11-17 | — | — | US | disclosed |
| US-6960679-B2 | Preparation of silyl ketene acetal and disilyl ketene acetal | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2005-11-01 | — | — | US | disclosed |
| US-20040215033-A1 | Preparation of silyl ketene acetal and disilyl ketene acetal | SHIN-ETSU CHEMICAL CO. LTD. (JP) | 2004-10-28 | — | — | US | disclosed |
| EP-1471069-A1 | Preparation of silyl ketene acetals and disilyl ketene acetals | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2004-10-27 | — | — | EP | disclosed |
| EP-0278668-A2 | Polymerisation process | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-08-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256329-A1 | Preparation of silyl ketene acetal and disilyl ketene acetal | TREH, DEGS1, PHYKPL | TSHR 3406/4885ESR1 2400/4885ESR2 1488/4885 |
| US-20040215033-A1 | Preparation of silyl ketene acetal and disilyl ketene acetal | TREH, PHYKPL, KAT8 | TSHR 3402/4885ESR1 2413/4885ESR2 2548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.