Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTN3A1 | O00481 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14107937 | 0.90 | BTN3A1 (0.34) | BTN3A1 | |
| SCHEMBL14107876 | 0.90 | BTN3A1 (0.34) | BTN3A1 | |
| SCHEMBL9010750 | 0.90 | ALDH1A1 (0.32) | — | |
| SCHEMBL9010766 | 0.89 | — | — | |
| SCHEMBL4742426 | 0.83 | THRB (0.32) | — | |
| SCHEMBL3561644 | 0.83 | THRB (0.32) | — | |
| SCHEMBL4742434 | 0.83 | THRB (0.32) | — | |
| SCHEMBL12883275 | 0.83 | THRB (0.32) | — | |
| SCHEMBL2687927 | 0.83 | THRB (0.32) | — | |
| SCHEMBL14107861 | 0.81 | CYP3A4 (0.32) | BTN3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188064-B2 | Reducing cell differentiation of adipocyte; reducing body fat | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-05-29 | — | — | US | disclosed |
| US-8058265-B2 | 1a-hydroxy-2-(3'-hydroxypropylidene)-19-nor-vitamin D compounds and methods of making and treatment thereof | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2011-11-15 | — | — | US | disclosed |
| US-7763598-B2 | 1α-hydroxy-2-(3′-hydroxypropylidene)-19-nor-vitamin D compounds with a 1,1-dimethylpropyl side chain | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2010-07-27 | — | — | US | disclosed |
| US-20090281340-A1 | 1ALPHA-HYDROXY-2-(3'-HYDROXYPROPYLIDENE)-19-NOR-VITAMIN D COMPOUNDS AND METHODS OF MAKING AND TREATMENT THEREOF | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2009-11-12 | — | — | US | disclosed |
| US-7531527-B2 | 2-Propylidene-19-nor-vitamin D compounds | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2009-05-12 | — | — | US | disclosed |
| US-20070244072-A1 | 1a-Hydroxy-2-(3'-Hydroxypropylidene)-19-nor-vitamin D compounds and methods of making and treatment thereof | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2007-10-18 | — | — | US | disclosed |
| US-20070238703-A1 | 1alpha-Hydroxy-2-(3'-Hydroxypropylidene)-19-Nor-Vitamin D Compounds with a 1,1-Dimethylpropyl Side Chain | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2007-10-11 | — | — | US | disclosed |
| US-20070213546-A1 | 2-Propylidene-19-nor-vitamin D compounds | WISCONSIN ALUMNI RESEARCH FOUNDATION. (US) | 2007-09-13 | — | — | US | disclosed |
| US-7241747-B2 | 2-propylidene-19-nor-vitamin D compounds | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2007-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213546-A1 | 2-Propylidene-19-nor-vitamin D compounds | VDR, CD14, CYP24A1 | BTN3A1 403/4885 |
| US-20070238703-A1 | 1alpha-Hydroxy-2-(3'-Hydroxypropylidene)-19-Nor-Vitamin D Compounds with a 1,1-Dimethylpropyl Side Chain | CYP24A1, CYP27B1, VDR | BTN3A1 112/4885 |
| US-20070244072-A1 | 1a-Hydroxy-2-(3'-Hydroxypropylidene)-19-nor-vitamin D compounds and methods of making and treatment thereof | CYP24A1, CYP2R1, VDR | BTN3A1 1426/4885 |
| US-20090281340-A1 | 1ALPHA-HYDROXY-2-(3'-HYDROXYPROPYLIDENE)-19-NOR-VITAMIN D COMPOUNDS AND METHODS OF MAKING AND TREATMENT THEREOF | CYP24A1, CYP2R1, VDR | BTN3A1 1218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.