Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.45 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3148903 | 1.00 | KDM4E (0.48) | KDM4EMAOBAOC3MRGPRX4PRMT5 | |
| SCHEMBL817449 | 1.00 | KDM4E (0.48) | KDM4EMAOBAOC3MRGPRX4PRMT5 | |
| SCHEMBL16168405 | 0.84 | KDM4E (0.49) | KDM4EMAOBAOC3MRGPRX4L3MBTL1 | |
| SCHEMBL12190635 | 0.82 | L3MBTL1 (0.48) | KDM4EMAOBAOC3MRGPRX4L3MBTL1 | |
| SCHEMBL4046553 | 0.80 | KDM4E (0.56) | KDM4EMAOBAOC3MRGPRX4L3MBTL1 | |
| SCHEMBL29847359 | 0.80 | KDM4E (0.56) | KDM4EMAOBAOC3MRGPRX4L3MBTL1 | |
| SCHEMBL19750630 | 0.80 | KDM4E (0.56) | KDM4EMAOBAOC3MRGPRX4L3MBTL1 | |
| SCHEMBL11518342 | 0.79 | MAOB (0.50) | KDM4EMAOBAOC3MRGPRX4L3MBTL1 | |
| SCHEMBL16414719 | 0.79 | TSHR (0.60) | KDM4EMAOBAOC3MRGPRX4PRMT5 | |
| SCHEMBL16414613 | 0.79 | TSHR (0.60) | KDM4EMAOBAOC3MRGPRX4PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1169467-A1 | PROCESS FOR THE PREPARATION OF PROSTAGLANDIN PRECURSORS | Chirotech Technology Limited (GB) | 2002-01-09 | — | — | EP | claimed |
| US-20010009770-A1 | Process for the preparation of prostaglandin precursors | FOX MARTIN EDWARD (GB) | 2001-07-26 | — | — | US | claimed |
| WO-2000061777-A1 | PROCESS FOR THE PREPARATION OF PROSTAGLANDIN PRECURSORS | CHIROTECH TECHNOLOGY LIMITED (GB) | 2000-10-19 | — | — | WO | claimed |
| EP-2274266-B1 | PROCESS FOR THE PREPARATION OF PROSTAGLANDIN ANALOGUES AND INTERMEDIATES THEREOF | SCINOPHARM TAIWAN LTD (TW) | 2014-10-15 | — | — | EP | disclosed |
| EP-1810967-B1 | Processes and intermediates for the preparations of prostaglandins | CHIROGATE INT INC (TW) | 2014-07-30 | — | — | EP | disclosed |
| US-8742143-B2 | Process for the preparation of prostaglandin analogues | SCINOPHARM TAIWAN, LTD. (TW) | 2014-06-03 | — | — | US | disclosed |
| US-20130211128-A1 | Process for the Preparation of Prostaglandin Analogues | SCINOPHARM TAIWAN LTD. (TW) | 2013-08-15 | — | — | US | disclosed |
| US-8436194-B2 | Process for the preparation of prostaglandin analogues and intermediates thereof | SCINOPHARM TAIWAN, LTD. (TW) | 2013-05-07 | — | — | US | disclosed |
| US-8436194-B2 | Process for the preparation of prostaglandin analogues and intermediates thereof | SCINOPHARM TAIWAN, LTD. (TW) | 2013-05-07 | — | — | US | disclosed |
| US-8030514-B2 | Processes and intermediates for the preparations of prostaglandins | CHIROGATE INTERNATIONAL INC. (TW) | 2011-10-04 | — | — | US | disclosed |
| US-20110130577-A1 | Process for the Preparation of Prostaglandin Analogues and Intermediates Thereof | SCINOPHARM TAIWAN LTD. | 2011-06-02 | — | — | US | disclosed |
| US-7511168-B2 | Processes and intermediates for the preparations of prostaglandins | Wei, Shih-Yi (TW) | 2009-03-31 | — | — | US | disclosed |
| US-20080039637-A1 | Processes and intermediates for the preparations of prostaglandins | CHIROGATE INTERNATIONAL INC. | 2008-02-14 | — | — | US | disclosed |
| US-20080039627-A1 | Processes and intermediates for the preparations of prostaglandins | CHIROGATE INTERNATIONAL INC. | 2008-02-14 | — | — | US | disclosed |
| EP-1810967-A1 | Processes and intermediates for the preparations of prostaglandins | Chirogate International Inc. (TW) | 2007-07-25 | — | — | EP | disclosed |
| US-20070167641-A1 | Processes and intermediates for the preparations of prostaglandins | CHIROGATE INTERNATIONAL INC. | 2007-07-19 | — | — | US | disclosed |
| EP-1169467-A1 | PROCESS FOR THE PREPARATION OF PROSTAGLANDIN PRECURSORS | Chirotech Technology Limited (GB) | 2002-01-09 | — | — | EP | disclosed |
| US-20010009770-A1 | Process for the preparation of prostaglandin precursors | FOX MARTIN EDWARD (GB) | 2001-07-26 | — | — | US | disclosed |
| US-6214611-B1 | PREPARATION OF A PROPARGYLIC ALCOHOL ENRICHED IN (R)-ENANTIOMER BY ESTERIFICATION OF RACEMIC ALCOHOL USING ACYL DONOR AND ENZYME, REMOVAL OF UNTREATED (S)-ALCOHOL, AND ENANTIOSELECTIVE HYDROLYSIS OF (R)-ESTER USING SECOND ENZYME | CHIROTECH TECHNOLOGY LIMITED (GB) | 2001-04-10 | — | — | US | disclosed |
| WO-2000061777-A1 | PROCESS FOR THE PREPARATION OF PROSTAGLANDIN PRECURSORS | CHIROTECH TECHNOLOGY LIMITED (GB) | 2000-10-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070167641-A1 | Processes and intermediates for the preparations of prostaglandins | PTGES, PTGER1, PTGIS | KDM4E 2828/4885MAOB 1085/4885AOC3 1786/4885 |
| US-20080039637-A1 | Processes and intermediates for the preparations of prostaglandins | PTGES, PTGER1, PTGIS | KDM4E 2828/4885MAOB 1085/4885AOC3 1786/4885 |
| US-20010009770-A1 | Process for the preparation of prostaglandin precursors | ADH1A, ADH1C, ADH5 | KDM4E 1615/4885MAOB 339/4885AOC3 250/4885 |
| US-20080039627-A1 | Processes and intermediates for the preparations of prostaglandins | PTGES, PTGER1, PTGIS | KDM4E 2828/4885MAOB 1085/4885AOC3 1786/4885 |
| US-20110130577-A1 | Process for the Preparation of Prostaglandin Analogues and Intermediates Thereof | PTGIS, PTGES, PTGER1 | KDM4E 4422/4885MAOB 1088/4885AOC3 2004/4885 |
| US-20130211128-A1 | Process for the Preparation of Prostaglandin Analogues | PTGIS, PTGES, PTGER1 | KDM4E 3794/4885MAOB 1473/4885AOC3 2196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.