Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | STK17B | O94768 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8181764 | 0.87 | CA2 (0.42) | CA2 | |
| SCHEMBL7987893 | 0.78 | CAPN1 (0.41) | STK17BCA2 | |
| SCHEMBL8172780 | 0.77 | GAA (0.47) | — | |
| SCHEMBL8312946 | 0.73 | CYP4F2 (0.39) | CA2BRD4 | |
| SCHEMBL8181370 | 0.73 | TYR (0.42) | — | |
| SCHEMBL11686246 | 0.71 | THRA (0.50) | MAOACISD1MAOB | |
| SCHEMBL11262445 | 0.71 | MDM2 (0.44) | MAOBCA2 | |
| SCHEMBL8181317 | 0.71 | AMY1A (0.41) | — | |
| SCHEMBL8315528 | 0.70 | CA2 (0.37) | MAOAMAOBCA2BRD4 | |
| SCHEMBL14261715 | 0.70 | CA2 (0.36) | STK17BCA2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000018745-A1 | OXAZOLIDINE DERIVATIVES FOR THE TREATMENT AND PREVENTION OF METABOLIC BONE DISORDERS | ROCHE DIAGNOSTICS GMBH (DE) | 2000-04-06 | — | — | WO | disclosed |