Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 9/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8181603 | 0.91 | MAPT (0.46) | METMAPTKMT2ACTSBTDP1 | |
| SCHEMBL8184659 | 0.91 | MAPT (0.45) | METMAPTKMT2ACTSBTDP1 | |
| SCHEMBL8179070 | 0.91 | MAPT (0.45) | METMAPTKMT2ACTSBTDP1 | |
| SCHEMBL8178194 | 0.90 | PDE4A (0.43) | METTSHRKMT2ATDP1KCNH2 | |
| SCHEMBL7018675 | 0.90 | MET (0.43) | METTSHRKMT2AKCNH2EPHX2 | |
| SCHEMBL8185534 | 0.90 | MAPT (0.45) | METMAPTKMT2ACTSBTDP1 | |
| SCHEMBL8178702 | 0.89 | CTNNB1 (0.45) | MAPTTSHRKMT2AEPHX2 | |
| SCHEMBL7013401 | 0.87 | MET (0.40) | METKCNH2 | |
| SCHEMBL8169893 | 0.85 | ALDH1A1 (0.47) | TSHRKMT2ATP53 | |
| SCHEMBL8170085 | 0.85 | CTNNB1 (0.48) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6130223-A | Thienopyrimidine with phosphodiesterase V inhibiting effect | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-10-10 | — | — | US | disclosed |