Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.42 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | RORB | Q92753 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8190570 | 0.76 | MAPT (0.42) | MAPTSMN1; SMN2RORBLMNAALOX15 | |
| SCHEMBL29463149 | 0.73 | LMNA (0.50) | MAPTCCNB2CCNE2CDK1CCNB1 | |
| SCHEMBL523863 | 0.72 | MAPT (0.49) | MAPTSMN1; SMN2CCNB2CCNE2CDK1 | |
| SCHEMBL8194073 | 0.68 | MAPT (0.48) | MAPTSMN1; SMN2LMNAALOX15KMT2A | |
| SCHEMBL24105612 | 0.66 | ALOX15 (0.49) | MAPTSMN1; SMN2CYP2C9LMNAALOX15 | |
| SCHEMBL30421622 | 0.66 | TP53 (0.66) | MAPTCYP2C9RORBLMNAALOX15 | |
| SCHEMBL9821675 | 0.66 | TP53 (0.66) | MAPTCYP2C9RORBLMNAALOX15 | |
| SCHEMBL15012670 | 0.66 | RORB (0.48) | RORBNOTUM | |
| SCHEMBL23294452 | 0.66 | KMO (0.47) | IDO1KMO | |
| SCHEMBL11755917 | 0.66 | SMN1; SMN2 (0.68) | MAPTSMN1; SMN2CYP2C9LMNAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6030926-A | AS HERBICIDE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2000-02-29 | — | — | US | disclosed |
| US-5939559-A | HERBICIDES FROM PYRAZOLE KETONES | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1999-08-17 | — | — | US | disclosed |
| EP-0822187-A1 | PYRAZOLE DERIVATIVES AND HERBICIDES | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1998-02-04 | — | — | EP | disclosed |