Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.47 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.47 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.47 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.47 |
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL523863 | 0.83 | MAPT (0.49) | LMNAALOX15CCNB2CCNE2CDK1 | |
| SCHEMBL8192196 | 0.73 | MAPT (0.42) | LMNAALOX15CCNB2CCNE2CDK1 | |
| SCHEMBL9148337 | 0.73 | LMNA (0.85) | LMNAALOX15HPGDSALDH1A1HPGD | |
| SCHEMBL182010 | 0.72 | CES2 (0.71) | LMNAALOX15HPGDSALDH1A1HPGD | |
| SCHEMBL257287 | 0.72 | HPGDS (0.55) | LMNAALOX15HPGDSALDH1A1HPGD | |
| SCHEMBL2656185 | 0.70 | HPGDS (0.49) | LMNAALOX15HPGDSALDH1A1HPGD | |
| SCHEMBL24554622 | 0.70 | KDM4E (0.53) | LMNAALOX15CDK2HPGDSALDH1A1 | |
| SCHEMBL27697492 | 0.69 | HPGDS (0.47) | LMNAALOX15HPGDSALDH1A1HPGD | |
| SCHEMBL11930062 | 0.68 | ALOX15 (0.64) | LMNAALOX15HPGDSALDH1A1HPGD | |
| SCHEMBL3859942 | 0.67 | ALOX15 (1.00) | LMNAALOX15HPGDSALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112876416-B | Diaryl formyl substituted pyrazole compound and preparation method thereof | 浙大城市学院 | 2022-03-29 | — | — | CN | claimed |